Results 191 to 200 of about 28,351 (266)

Environmental Enrofloxacin Exposure as a Modifiable Driver of Mitochondria‐Mediated Intestinal Aging and Barrier Dysfunction

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
Environmentally relevant enrofloxacin accelerates intestinal aging by impairing epithelial mitochondrial function, disrupting barrier integrity, and reshaping the gut microbiota. Mitochondrial restoration with pyrroloquinoline quinone alleviates hypoxia, inflammation, and gut damage.
Kan Yu   +10 more
wiley   +1 more source

Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma

open access: yesAllergy, Volume 81, Issue 5, Page 1571-1586, May 2026.
Complement activation module, particularly C5, is positively associated with eosinophilic inflammation in severe asthma cohorts. Elevated C5 expression correlates with poor lung function improvement and persistent eosinophilic inflammation. Mouse model studies confirm that C5 exacerbates eosinophilic inflammation, highlighting its potential as a ...
Cong Dong   +217 more
wiley   +1 more source

Chinese Position Paper on Biologic Therapy for Allergic Rhinitis

open access: yesAllergy, Volume 81, Issue 5, Page 1354-1369, May 2026.
ABSTRACT Allergic rhinitis (AR) is a common, persistent nasal disorder that poses significant public health challenges worldwide. Current treatment options frequently fail to achieve adequate symptom control in a substantial subset of patients. Over the past two decades, biologic therapies that target type 2 inflammatory pathways have been used to ...
Yuan Zhang   +37 more
wiley   +1 more source

Home‐Based Learning Opportunities, Responsive Caregiving and the Development of Preschool‐Aged Children in Low‐ and Middle‐Income Countries of the East Asia and Pacific Region: A Systematic Review

open access: yesChild: Care, Health and Development, Volume 52, Issue 3, May 2026.
ABSTRACT Background Optimal early childhood development predicts lifelong health and well‐being. A child's immediate environment, especially the home, shapes cognitive, physical, language, motor, social and emotional development. Contextually relevant data on the proximal settings that support preschool‐aged children are lacking in low‐ and middle ...
Sally Popplestone   +5 more
wiley   +1 more source

Ethical Challenges and Strategies in Nursing Doctoral Supervision: A Systematic Mixed‐Method Review

open access: yesJournal of Advanced Nursing, Volume 82, Issue 5, Page 4167-4184, May 2026.
ABSTRACT Aim To identify and address ethical challenges in doctoral supervision within nursing and health sciences and propose strategies to overcome them. Design Following PRISMA guidelines, this mixed‐method systematic review synthesises findings from quantitative, qualitative and mixed‐methods studies published in English between 2014 and 2025 ...
Tove Godskesen   +3 more
wiley   +1 more source

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