Results 181 to 190 of about 4,280,969 (314)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Research reports of the Environmental Monitoring and Support Laboratory-Las Vegas.

open access: yes
Mode of access ...
Environmental Monitoring and Support Laboratory (Las Vegas, Nev.).
core  

The readiness-preparedness bias: recalibrating monitoring logic. [PDF]

open access: yesFront Physiol
Kruczek K, Rebelo A, Gabbett T, Nowak M.
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Research Progress, Potential Environmental Impacts in Marine Geoengineering and Management Recommendations in China

open access: yesHaiyang Kaifa yu guanli
Marine geoengineering has garnered considerable attention as a promising avenue for climate change mitigation. Within its two principal branches, research on marine carbon dioxide removal (CDR) has demonstrated substantial progress as demonstrated by a ...
WEI Shuyun   +5 more
doaj  

Bringing early detection to life: real-world operationalization of a presymptomatic type 1 diabetes screening and monitoring pilot program. [PDF]

open access: yesBMJ Open Diabetes Res Care
Demeterco-Berggren C   +11 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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