Results 181 to 190 of about 5,419 (294)

Effect of Intraoperative Nerve Monitorization on Predicting Vocal Cord Paralysis in Thyroid Surgery. [PDF]

Int Arch Otorhinolaryngol
Yalçıner B, Bayır Ö, Kızılgül M, Uçan B, Saylam G, Tatar EÇ, Çakal E, Tokgöz SA, Akyıldız İ, Korkmaz MH.   +9 more
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Exploring donor-derived cell-free DNA as a rejection biomarker during uterus transplant follow up. [PDF]

Commun Med (Lond)
González-Roca E, Rius M, Ramírez-Bajo MJ, Montalbán-Casafont A, Bañón-Maneus E, Hierro-García N, Musquera M, Saco A, Alcaraz A, Brunet M, Palou E, Diekmann F, Carmona F, Puig-Butillé JA.   +13 more
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Investigating hepatic fibrosis heterogeneity by three-dimensional imaging in metabolic dysfunction-associated steatotic liver disease. [PDF]

Sci Rep
Yigit B, Ozgonul E, Yaman O, Sipahioglu T, Ulukan B, Cetin Tas Y, Morova B, Aydin M, Uysalli Y, Demirtas E, Erkan M, Tellioglu G, Atak D, Gursoy Ozdemir Y, Karahuseyinoglu S, Yurdaydin C, Akyildiz M, Sheth A, Aithal GP, Kirimlioglu H, Dayangac M, Ferhanoglu O, Kiraz A, Zeybel M.   +23 more
europepmc   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Global Perspective of CKD: Chile. [PDF]

Kidney360
Toro L, Lorca E, Bórquez T, Chilean Society of Nephrology.   +3 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Prognostic Value of Serial Lactate Measurement in Pediatric Cardiac Surgery Patients with Congenital Heart Disease in Southeast Mexico. [PDF]

Med Sci (Basel)
Sanchez-Felix E, Olivera-Mar A, Santaularia-Tomas M, Johnson-Herrera J, Ortiz-Vera L, Perez-Navarrete A, Rivero-Peraza M, Mendez-Dominguez N.   +7 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source