Results 231 to 240 of about 5,419 (294)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

open access: yesFEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar   +11 more
wiley   +1 more source

Sudden Cardiac Arrest in an Adolescent with X-Linked Ichthyosis. [PDF]

open access: yesAnatol J Cardiol
Mutlu H   +6 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Telemedicine and the European Health Data Space: a new paradigm for healthcare in the EU. [PDF]

open access: yesFront Digit Health
Carradinha M   +11 more
europepmc   +1 more source

Exploring the potential of natural history studies for rare neurological diseases. [PDF]

open access: yesAnn Med Surg (Lond)
Muili AO   +7 more
europepmc   +1 more source

Magnetic field in the extreme low frequency band protects neuronal and microglia cells from oxygen-glucose deprivation. [PDF]

open access: yesFront Cell Neurosci
Mata P   +9 more
europepmc   +1 more source

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