A rhesus macaque model of α‐dystroglycanopathy caused by a POMT1 splice altering variant
Rhesus macaques homozygous for a naturally occurring spice altering variant in the POMT1 gene develop lissencephaly, microphthalmia, and muscular contracture. The presentation models severe presentation of the human Walker‐Warburg syndrome. Abstract Background Biallelic mutations in genes associated with α‐dystroglycan glycosylation manifest in a ...
Anya Nordlund +7 more
wiley +1 more source
Anemia of inflammation is a highly prevalent secondary anemia complicating chronic inflammatory diseases. Current animal models are categorized into sterile inflammation, disease‐specific, and genetically engineered models, with comparative analysis of their modeling principles, characteristic phenotypes, and translational advantages to elucidate core ...
Jiayi Cheng +4 more
wiley +1 more source
Bispecific antibodies that engage pIgR enrich in mucosa in cynomolgus monkeys. [PDF]
Marks K +13 more
europepmc +1 more source
PbAT: A user‐friendly R/Shiny platform for data‐driven decision support in crop improvement
Abstract Premise Modern plant breeding requires robust analysis of complex, multi‐environment datasets to identify superior genotypes. Although R offers powerful statistical packages, their use often requires programming expertise. Existing graphical user interface (GUI)‐based tools are either limited in scope or not openly accessible, leaving breeders
Krishnan P. Abhijith +6 more
wiley +1 more source
Abstract Muscle architecture is a major determinant of muscle performance and, in mammalian lineages, has been correlated with both feeding ecology and locomotor behaviors. Over the past decade, contrast‐enhanced micro‐CT (DiceCT) has emerged as an alternative to traditional dissection‐based measurement.
Aleksandra Ratkiewicz +5 more
wiley +1 more source
Dose-dependent power and connectivity modulation of low frequency oscillations through transcranial magnetic stimulation in non-human primates. [PDF]
Güth MR +8 more
europepmc +1 more source
Abstract In a large sample of adult crab‐eating macaques, we quantified sexual dimorphism in size, shape, and covariance across the whole skull and among anatomical regions of the cranium and mandible. All regions showed significant mean sex differences, but the magnitude of size and shape dimorphism varied substantially.
Andrea Cardini, Paul O'Higgins
wiley +1 more source
Functional analysis of adrenocorticotropic-hormone-producing pituitary cells derived from human pluripotent stem cells in murine and primate models of hypopituitarism. [PDF]
Kondo T +21 more
europepmc +1 more source
The petrotympanic canal (Huguier canal): Evolutionary, anatomical, and medical perspectives
Abstract The petrotympanic canal, traditionally referred to as Civinini's or Huguier's canal, represents an anatomical passage connecting the middle ear and temporomandibular joint (TMJ). Despite its early description, its structural complexity and functional significance have often been underestimated. In this study, we combined historical, anatomical,
Andrea Papini +8 more
wiley +1 more source
Metaheuristic-driven automatic ARIMA order selection using spider monkey optimization for agricultural production forecasting. [PDF]
Kumar A +12 more
europepmc +1 more source

