Results 151 to 160 of about 155,515 (267)

Autologous Iliac Crest Bone Graft After Anterior Cruciate Ligament Reconstruction Failure in Patients With Both Femoral and Tibial Tunnel Enlargement

open access: yesArthroscopy Techniques, EarlyView.
Abstract Tunnel enlargement is a common challenge in revision anterior cruciate ligament reconstruction and compromises graft fixation and biological integration. Traditional 2‐stage revision procedures prolong treatment duration and increase patient morbidity.
Aoqiu Wu   +4 more
wiley   +1 more source

Arthroscopic Fixation of Unstable Adolescent Knee Osteochondritis Dissecans With Structural Tibial Cancellous Bone Autograft

open access: yesArthroscopy Techniques, EarlyView.
Abstract The treatment of knee osteochondritis dissecans in young patients remains challenging. Unstable or displaced lesions and those unresponsive to conservative management require surgical treatment. Because the articular surface morphology is complex and patient‐specific, preservation and fixation of the native osteochondritis dissecans fragment ...
Yuta Tachibana   +6 more
wiley   +1 more source

C-Reactive Protein as a Biomarker of Inflammation and Graft Injury After Kidney and Heart Allo- and Xenotransplantation Into Non-Human Primates. [PDF]

open access: yesXenotransplantation
Zaletel T   +13 more
europepmc   +1 more source

All‐Arthroscopic Trochlear Osteochondral Scaffold Matrix Implantation for Osteochondral Defects of the Femoral Trochlea

open access: yesArthroscopy Techniques, EarlyView.
Abstract The treatment of osteochondral defects via an aragonite‐based osteochondral scaffold has been established via mini‐arthrotomy. This report describes a variation of the established procedure to perform and complete the scaffold implantation in the femoral trochlea via a reproducible, all‐arthroscopic technique.
Matthew Varacallo, Jared Ham
wiley   +1 more source

Navigating adverse immunostimulation: A practical guide for clinical researchers

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort   +3 more
wiley   +1 more source

The Monkey's Paw

open access: yesEmerging Infectious Diseases, 2011
openaire   +2 more sources

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Problem setting The emergence of therapeutic proteins has coincided with an increase of acute adverse immunostimulation (AIS). AIS has occured in clinical trials despite compliance with regulatory guidelines on preclinical evaluation and its incidence is anticipated to increase even further.
Juliette A. van den Noort   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy