Results 281 to 290 of about 540,107 (356)

Gamma Irradiation of Poly(lactide‐co‐glycolide) Scaffolds Reduces the Mechanical Stability and Function of Islet Grafts in Diabetic Nonhuman Primates

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Clinical islet transplantation has long been investigated as a potential cure for type 1 diabetes (T1D), yet standard intrahepatic delivery leaves islets prone to an instant blood‐mediated inflammatory response. Herein, we investigated the design of microporous poly(D,l‐lactide‐co‐glycolide) (PLG) scaffolds for extrahepatic islet ...
Jessica L. King, Christopher Spencer, Richard Youngblood, Kelly Crumley, Elizabeth Bealer, Peter D. Rios, Ira Joshi, Sofia Ghani, Douglas Isa, James J. McGarrigle, David Cook, Conor Locke, Adam Abraham, Andrea Clark, José Oberholzer, Lonnie D. Shea   +15 more
wiley   +1 more source

Postnatal Development of the Perirhinal and Parahippocampal Cortices: A Stereological Study in Macaque Monkeys. [PDF]

J Comp Neurol
Villard J, Chareyron LJ, Banta Lavenex P, Amaral DG, Lavenex P.   +4 more
europepmc   +1 more source

Lab‐Scale Continuous Biomanufacturing: A Tool for Process Development With Adaptive Strategies for Capture and Virus Inactivation

Biotechnology and Bioengineering, EarlyView.
Schematic representation of the continuous lab‐scale process. ABSTRACT Monoclonal antibodies (mAbs) are nowadays fundamental in treating a wide range of severe diseases, including cancer, infections, or autoimmune disorders. Due to their high specificity, potent activity, and fewer side effects compared to small molecular drugs, the market for mAbs is ...
Thomas Kruse, Fabian Schmitz, Janina Kilian, Jonas Austerjost, Lucas‐Nik Reger, Markus Kampmann   +5 more
wiley   +1 more source

Expression of Dystroglycanopathy-Related Enzymes, POMGNT2 and POMGNT1, in the Mammalian Retina and 661W Cone-like Cell Line. [PDF]

Biomedicines
Quereda C, Gómez-Vicente V, Palmero M, Martín-Nieto J.   +3 more
europepmc   +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

The impact of urbanisation on social behaviour: a comprehensive review

Biological Reviews, EarlyView.
ABSTRACT Urbanisation is a key driver of global environmental change and presents animals with novel stressors and challenges. It can fundamentally influence social behaviour and has the potential to reshape within‐ and between‐species social interactions. Given the role of social behaviour in reproductive fitness and survival, understanding how social
Avery L. Maune, Barbara A. Caspers, Isabel Damas‐Moreira   +2 more
wiley   +1 more source

Characterization of a Long-Acting Anti-Human MASP-2 Antibody for the Treatment of Complement-Related Diseases. [PDF]

J Inflamm Res
Han X, Yang C, Wang Z, Fan K, Liu K, Ye H, Zhang W, Zhang J, Hu X, Lin H, Liao C.   +10 more
europepmc   +1 more source

Molecular bases of insect odorant receptor function: specificity and evolution

Biological Reviews, EarlyView.
ABSTRACT Insect odorant receptors (ORs) are a class of chemoreceptors that insects use to detect volatile cues in their environment. In recent years, major advances in the field of structural biology have made it possible to obtain the first structures of insect ORs.
Zibo Li, Abhinob Baruah, Sridevi Bhamidipati, Nicolas Montagné, Emmanuelle Jacquin‐Joly, Camille Meslin   +5 more
wiley   +1 more source

Prefrontal cortex temporally multiplexes slow and fast dynamics in value learning and memory. [PDF]

Nat Commun
Hashemirad SR, Abbaszadeh M, Ghazizadeh A.   +2 more
europepmc   +1 more source