Abstract Background Parkinson's Disease (PD) is a progressive neurodegenerative disorder primarily characterized by motor symptoms such as tremors, rigidity, and bradykinesia. Structural brain changes, including atrophy in the midbrain, basal ganglia, and cortical regions such as the frontal and temporal lobes, are observed in advanced stages.
Suraiya Mangra +5 more
wiley +1 more source
Transient rapamycin treatment avoids unwanted host immune responses toward AAV-delivered anti-HIV antibodies. [PDF]
Fuchs SP +16 more
europepmc +1 more source
Medical management of inflammatory bowel disease in a spider monkey [PDF]
Ramiro Isaza +2 more
openalex +1 more source
Long-term effects of forty-hertz auditory stimulation as a treatment of Alzheimer's disease: Insights from an aged monkey model study. [PDF]
Wang W +12 more
europepmc +1 more source
Convergence Deficits in Myoclonus‐Dystonia Point to Cerebellar Impairment
Abstract Background Myoclonus‐dystonia (M‐D) is a monogenic movement disorder, with proposed cerebellar dysfunction. Vergence eye movement deficits, characteristics of degenerative cerebellar disease, have not been studied in M‐D. Cerebellar transcranial alternating current stimulation (tACS) is considered a potential therapeutic approach.
Skadi Gerkensmeier +13 more
wiley +1 more source
Computational Fluid Dynamics Modeling of Intravitreal Ranibizumab Bolus Versus Subretinal ABBV-RGX-314 Transgene Product in Human Eyes. [PDF]
Park J, Kazemi M, Tamhane M, Shen J.
europepmc +1 more source
2D/3D CMR tissue tracking versus CMR tagging in the assessment of spontaneous T2DM rhesus monkeys with isolated diastolic dysfunction [PDF]
et al,, Zheng, Jie
core +1 more source
Morphological Changes in Direct Pathway Striatal Neurons in a Rat Model of Tardive Dyskinesia
Abstract Background Tardive dyskinesia (TD) and drug‐induced parkinsonism (DIP) arise from prolonged dopamine antagonist use. Although D2 receptor hypersensitivity in the indirect pathway is a proposed mechanism, the role of the direct pathway remains unclear.
Hiroki Hikichi +6 more
wiley +1 more source

