Results 41 to 50 of about 255,919 (307)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Acute respiratory viral infections in monkeys

Вопросы вирусологии
Acute respiratory viral infections (ARVI) are one of the most significant infections affecting the breeding of monkeys, especially among imported and captive primates.
Dmitry I. Dogadov, Karen K. Kyuregyan, Albert A. Minosyan, Aleksandra M. Goncharenko, Elena V. Shmat, Mikhail I. Mikhailov   +5 more
doaj   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

The enriched mind: cognitive stimulation and behavior in non-human primates

Frontiers in Veterinary Science
Non-human primates (NHPs) possess high cognitive abilities that enable them to respond effectively to complex social, ecological, and psychological challenges.
Daniel Mota-Rojas, Alexandra L. Whittaker, Genaro A. Coria-Avila, Adriana Domínguez-Oliva, Cécile Bienboire-Frosini, Ismael Hernández-Avalos, Cuauhtémoc Chávez, Adriana Olmos-Hernández, Julio Martínez-Burnes, Ricardo García-Herrera, Patricia Mora-Medina, Temple Grandin   +11 more
doaj   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

The Years of the Monkey [PDF]

Cell Research, 2013
The fact that mammals are diploid sets a barrier to rapidly understand the function of non-coding and coding genes in the genome. Recently, Yang et al. reported successful derivation of monkey haploid embryonic stem cells from parthenotes, which provide an effective platform for studying mammalian gene function and enable reverse genetic screening of ...
Xiaojun, Lian, Kenneth R, Chien
openaire   +2 more sources

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source

Gut microbiota and bacterial associations in monkeys with gastrointestinal diseases in the setting of helminth infestation

Ветеринария сегодня
One of the topical issues of current primatology is spontaneous pathology in monkeys, primarily gastrointestinal infections, which are the leading ones in the morbidity and mortality patterns of the animals raised in captivity. Gastrointestinal pathology
V. A. Kalashnikova, T. P. Egorova, A. V. Demerchyan, V. I. Polyakova, Y. I. Lenshina, D. A. Ilyazyants, I. M. Arshba   +6 more
doaj   +1 more source

Bartonella quintana Infections in Captive Monkeys, China

Emerging Infectious Diseases, 2011
Bartonella quintana has been considered to be specifically adapted to humans. Our isolation of the organism from 2 of 36 captive rhesus macaques in China and finding antibodies against B.
Ruting Huang, Qiyong Liu, Genping Li, Dongmei Li, Xiuping Song, Richard J. Birtles, Fan Zhao   +6 more
doaj   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source