Results 81 to 90 of about 255,919 (307)

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

Advanced Science, EarlyView.
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

A complicated form of spontaneous aortic atherosclerosis in an African green monkeys (Chlorocebus aethiops sabaeus) male. Clinical case

Revista Científica
Atherosclerosis is the mechanistic basis of cardiovascular disorders manifested by damage to the walls of the aorta, coronary, cerebral and peripheral arteries, leading to the development of acute or chronic ischemia of internal organs and tissues. This
Sergey Orlov, Andrey Panchenko, Viktor Shestakov, Artem Oganesian, Yulia Kolesnik, David Ilyazyants, Elena Radomskaya, Tamara Fedotkina, Dmitry Bulgin, Leonid Churilov   +9 more
doaj   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

‘There is no concern of prohibition against their trade’: A responsum by Rashbatz on the trade in monkeys practiced by Algerian Jews in the middle ages

HTS Teologiese Studies/Theological Studies, 2018
The current study deals with the responsum of R. Shimon ben Zemah Duran (Rashbatz, Algeria, 15th century), a Jewish halakhic adjudicator, on the trade in monkeys practiced by Algerian Jews in the middle ages.
Abraham O. Shemesh
doaj   +1 more source

Chemotherapy of second stage human African trypanosomiasis : comparison between the parenteral diamidine DB829 and its oral prodrug DB868 in vervet monkeys [PDF]

, 2015
Human African trypanosomiasis (HAT, sleeping sickness) ranks among the most neglected tropical diseases based on limited availability of drugs that are safe and efficacious, particularly against the second stage (central nervous system [CNS]) of ...
Wang, Michael Z., Shelley Ching, Bridges, Arlene S., Bridges, Arlene S, Wang, Michael Z, Gem, Charles O, Michael Z Wang, Wolf, Kristina K, Wang, Michael Zhuo, Wolf, Kristina K., Ching, Shelley, Mutuku, James N., Arlene S Bridges, Boykin, David W, Murilla, Grace A, Murilla, Grace A., Qiang Liu, Paine, Mary F., Boykin, David W., Grace A Murilla, Jones, Susan K, Charles O Gem, James N Mutuku, Mary F Paine, Susan K Jones, Richard R Tidwell, Mutuku, James N, Paine, Mary F, David W Boykin, Liu, Qiang, Tidwell, Richard R., John K Thuita, Gem, Charles O., Kristina K Wolf, Jones, Susan K., Brun, Reto, Thuita, John K., Boykin, David, Reto Brun, Piane, Mary F., Tidwell, Richard R, Thuita, John K, Mutuku JN, Ching S, Wolf KK, Brun Reto, Mutuku James N., Bridges AS, Gem CO, Tidwell RR, Boykin DW, Paine MF, Bridges Arlene S., Ching Shelley, Murilla GA, Tidwell Richard R., Liu Q, Wang MZ, Boykin David W., Thuita JK, Gem Charles O., Liu Qiang, Jones SK, Jones Susan K., Brun R, Wang Michael Z., Murilla Grace A., Wolf Kristina K., Thuita John K., Paine Mary F.   +69 more
core   +2 more sources

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

[News Clip: Space monkeys]

, 1960
Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news story about one of five monkeys that was sent to space.
WBAP-TV (Television station : Fort Worth, Tex.)
core   +1 more source

What Do Monkeys Eat? Diet Of Monkeys

, 2023
Are you curious about what monkeys eat? Do you ever wonder if they only eat bananas, like the stereotype suggests? Let's delve into the captivating world of monkey diets and explore what these intelligent creatures actually consume.
Erzsebet Frey
core   +1 more source

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

Advanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang, Jiani Deng, Man Yee Cheung, Tingting Fu, Xufeng Qi, Dongqing Cai, Jianmin Sun, Gang Lu, Peng Shi, Wai‐Yee Chan, Xu Li, Hui Zhao   +11 more
wiley   +1 more source

Hydroclimatic variability is associated with gastrointestinal parasite dynamics in black-horned capuchins (Sapajus nigritus cucullatus) in the Atlantic Forest of Argentina

Frontiers in Veterinary Science
Understanding the environmental drivers of parasite dynamics in wildlife is critical for predicting disease risk under changing climatic conditions. We investigated the relationship between climatic variables and patterns of gastrointestinal parasitism ...
Gimena Illia, Martin Kowalewski, Felix Ignacio Contreras, Thomas R. Gillespie, Karen E. DeMatteo, Karen E. DeMatteo, Luciana Oklander, Luciana Oklander   +7 more
doaj   +1 more source