Results 121 to 130 of about 36,008 (205)

MAO-A and the EEG Recognition Memory Signal in Left Parietal Cortex [PDF]

, 2014
A key part of episodic memory, or memory for the events of our lives, is recognition memory. Recognition memory is the ability to remember previously encountered stimuli.
Curran, Tim, Fisher, Claire M, Nyhus, Erika, Ross, Robert   +3 more
core   +1 more source

3,4‐Methylenedioxymethamphetamine (MDMA) does not induce robust psychomotor activation and 50‐kHz ultrasonic vocalisations in tryptophan hydroxylase 2 (Tph2)‐deficient rats lacking serotonin in the central nervous system

British Journal of Pharmacology, EarlyView.
Background and Purpose 3,4‐Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy, is a psychostimulant with entactogenic properties and known to induce arousal and euphoria. As an amphetamine derivate, MDMA acts on the monoamine systems in the brain and stimulates release of dopamine (DA), noradrenaline (NA) and serotonin (5‐HT), yet their ...
Tianhua Wang, Rainer K. W. Schwarting, Markus Wöhr   +2 more
wiley   +1 more source

Bexicaserin for the treatment of seizures in developmental and epileptic encephalopathies: A phase 1b/2a trial (PACIFIC)

Epilepsia, EarlyView.
Abstract Objective This randomized, double‐blind, phase 1b/2a clinical trial was designed to evaluate the safety, tolerability, and efficacy of oral bexicaserin versus placebo for the treatment of seizures in adolescents and adults with developmental and epileptic encephalopathies (DEEs).
Dennis J. Dlugos, Ingrid E. Scheffer, Jacqueline A. French, David G. Vossler, Chad Orevillo, Shikha Polega, Randall Kaye, and the LP352‐201 Study Investigators, Kore Liow, Ena Zhu, Jennifer Waldron, Hayley Groubert, Alexis Anderson, Pavel Klein, Salman Hashmi, Shicong Ye, Anita Farhi, David Vossler, Dione M. Froman, Shannon L. Hoffman‐Huffaker, Ki Hyeong Lee, AnnaLyn Dallas, Amir Arain, Laura Beeler, Michael Macken, Irena Bellinski, Elizabeth Cunningham, James Renfroe, Shezsay Colbert, Robert Hogan, Patty Schaefer, Susan Shaw, Sheetal Desai, Ahmed Sadek, Haile Robertson, Kamil Detyniecki, Anabela Cieslicki, Ruben Kuzniecky, Sarah Goodman, Selim Benbadis, Marina Azevedo, Sami Aboumatar, Julie Biel, Nilika Singhal, Emerald Wan, Evan Fertig, Hannah Hart, Debopam Samanta, Sarah Hankins, Steven Wolf, Patricia Pena, Robert Nahouraii, M. J. Mari, David Burdette, Stephanie Mueller, Karen Keough, Victoria Henderson, Talitha Durgin, Terence O’Brien, Rafael Smith, Jack Germaine, Kate Riney, Lori Anthony, David Reutens, Kimberley Irwin, Michael Fahey, Melissa Batt, Stephanie Kaladis, Kasthoori Jeyachanthiran, Ingrid Scheffer, Rebecca Wharrie, Greesha Zacharia, Brittany Walsh, Heather Robinson, Sharon Ganter   +74 more
wiley   +1 more source

Saccharomyces cerevisiae Yeast‐Based Supplement and Breast Milk Supply: A Randomised Placebo‐Controlled Trial

Maternal &Child Nutrition, EarlyView.
Maternal brewer's yeast supplementation did not change the milk oligosaccharide (HMO) concentration, but more mothers felt their milk supply was increased, and fewer reported formula use by 6 months postpartum compared to those taking the placebo. This suggests the supplement may support breastfeeding, warranting further investigation in larger trials.
Lili Jia, Louise Brough, Janet L. Weber
wiley   +1 more source

Referred Pain Manifestation and Its Impact on Patients With Temporomandibular Disorder

Oral Diseases, EarlyView.
ABSTRACT Objective To investigate whether a higher number of sites eliciting referred pain upon palpation is associated with greater impairment in biopsychosocial aspects in TMD patients and identify variables that predict increased referred pain. Methods This cross‐sectional study analyzed data from 77 women with myalgia, assessing the number of sites
Beatriz Amaral de Lima‐Netto, Paulo César Rodrigues Conti, Rafaela Stocker Salbego, Matheus Herreira‐Ferreira, Yuri Martins Costa, Leonardo Rigoldi Bonjardim   +5 more
wiley   +1 more source

Returning the Gift: The Emerging Politics of Toto, Blood and Plasma

Kōtuitui: New Zealand Journal of Social Sciences Online, Volume 21, Issue 1, March 2026.
This article investigates key ethical issues arising as part of the LiLACS NZ study, a study of Māori and non‐Māori living into advanced age. LiLACS NZ is the first longitudinal study of advanced ageing in the world that has an Indigenous cohort. In this article, we explore several key issues relating to the concepts of privacy and data access that ...
Marama Muru‐Lanning, Jade Farley, Nicholas Jones   +2 more
wiley   +1 more source

Evaluation of the Use of a Medium Cut‐Off Dialyser Theranova 400 for Severe Metaldehyde Intoxication in Three Dogs: Dialytic Clearance and Therapeutic Response

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
Three dogs with severe neurological signs from acute metaldehyde intoxication were treated with emergent haemodialysis using a medium cut‐off (MCO) dialyser. Neurological signs resolved within a single 4‐h session without adverse effects. Dialytic clearance of metaldehyde was 12.5 times higher than intrinsic clearance, demonstrating the clinical ...
Maxime Rodary, Claudia Iannucci, Andreas F. Lehner, Birgit Puschner, John P. Buchweitz, Alessio Vigani   +5 more
wiley   +1 more source

Neurogenic Stuttering and Lateralized Motor Deficits Induced by Tranylcypromine

Behavioural Neurology, 1994
A case of neurogenic stuttering induced by the monoamine oxidase inhibitor tranylcypromine is described. The association of neurogenic stuttering with acquired lateralized motor deficits in the patient described is discussed with reference to current ...
J. D. Duffy
doaj   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

From Struggling (With) Screening Tests to Mouse Models of Depression‐Relevant Neurobehavioral States

Current Protocols, Volume 6, Issue 2, February 2026.
Abstract A major, serendipitous psychiatric discovery is monoamine‐transporter reuptake inhibition as an antidepressant mechanism of action. Chronic treatment with such antidepressants is efficacious, with onset requiring 1‐2 weeks, in many but by no means all patients with major depressive or another stress‐related neuropsychiatric disorder.
Christopher R. Pryce
wiley   +1 more source