Results 151 to 160 of about 36,008 (205)
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Archives of General Psychiatry, 1979
Data from double-blind, placebo-controlled trials of the monoamine oxidase (MAO) inhibitors show that phenelzine is clearly effective in neurotic or atypical depressives, but the findings concerning its effect in endogenous depressives are inconclusive.
F, Quitkin, A, Rifkin, D F, Klein
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Data from double-blind, placebo-controlled trials of the monoamine oxidase (MAO) inhibitors show that phenelzine is clearly effective in neurotic or atypical depressives, but the findings concerning its effect in endogenous depressives are inconclusive.
F, Quitkin, A, Rifkin, D F, Klein
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Monoamine oxidase A and monoamine oxidase B activities are catalyzed by different proteins
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1985Monoamine oxidases A and B (amino: oxygen oxidoreductase (deaminating) (flavin-containing), EC 1.4.3.4) have been identified in the outer membranes of rat liver mitochondria by their covalent reaction with the inhibitor, [3H]pargyline. On analysis by polyacrylamide gel electrophoresis under denaturing conditions.
D, Smith, C, Filipowicz, R, McCauley
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Monoamine Oxidase Inhibitors and Neuroprotection
American Journal of Therapeutics, 2012Monoamine oxidase inhibitors have been available for more than 50 years, initially developed as antidepressants but currently used in a variety of psychiatric and neurological conditions. There has been a recent surge of interest in monoamine oxidase inhibitors because of their reported neuroprotective and/or neurorescue properties.
Saleem K, Al-Nuaimi +2 more
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Styrene inhibits monoamine oxidase A, but not monoamine oxidase B in monkey brain mitochondria
Toxicology Letters, 2000The effects of styrene on mitochondrial monoamine oxidase (MAO) activity in rat and monkey brains were compared in vitro. After preincubation at 25 degrees C for 20 min with 1 mM styrene monomer MAO-A activity in monkey brain was inhibited potently using 5-HT (for MAO-A substrate), but MAO-B activity in monkey brain and platelets were slightly ...
T, Egashira +3 more
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European Journal of Neuroscience, 2006
AbstractAlthough nicotine is considered to be responsible for the addictive properties of tobacco, growing evidence underlines the importance of non‐nicotine components in smoking reinforcement. It has been shown that tobacco smoke contains monoamine oxidase (MAO) A and B inhibitors and decreases MAO‐A and MAO‐B activity in smokers.
Karine, Guillem +6 more
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AbstractAlthough nicotine is considered to be responsible for the addictive properties of tobacco, growing evidence underlines the importance of non‐nicotine components in smoking reinforcement. It has been shown that tobacco smoke contains monoamine oxidase (MAO) A and B inhibitors and decreases MAO‐A and MAO‐B activity in smokers.
Karine, Guillem +6 more
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A convenient spectrophotometric assay for monoamine oxidase
Analytical Biochemistry, 1969Abstract A rapid, convenient, and sensitive assay of monoamine oxidase activity in whole homogenates and partially purified preparations of monoamine oxidase has been developed. The assay depends upon the production of p-dimethylaminobenzaldehyde (ϵ = 2.77 × 104 at 355 mμ) from p-dimethylaminobenzylamine. Although the substrate is oxidized at a lower
R A, Deitrich, V G, Erwin
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Monoamine Oxidase-A Deficiency
2011Abstract This chapter provides pictures and clinical details of MONOAMINE OXIDASE-A ...
Roger E. Stevenson +2 more
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A sensitive photometric assay for monoamine oxidase
Analytical Biochemistry, 1978Abstract A new spectrophotometric assay for the determination of monoamine oxidase activity is described. This simple and sensitive method is based on a coupled indicator reaction measuring the monoamine oxidase-dependent production of hydrogen peroxide.
H, Köchli, J P, Von Wartburg
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Kinetic mechanism of monoamine oxidase A
Biochemistry, 1991Steady-state kinetic data for monoamine oxidase A in crude extracts suggest an exclusively ping-pong mechanism, in contrast to those for monoamine oxidase B, which indicate alternate mechanisms involving either a binary or ternary complex. In this study, with use of purified monoamine oxidase A, steady-state data for the inhibition by D-amphetamine of ...
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Brain monoamine oxidase and aging: A review
Archives of Gerontology and Geriatrics, 1992The present state of research on the age-related dynamics of brain monoamine oxidase (MAO) activity and its role in the development of age pathology is described. Special attention is given to the role of MAO in the pathogenesis of parkinsonism and to the mechanisms of its interaction with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), a possible
S G, Burchinsky, S M, Kuznetsova
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