Results 161 to 170 of about 36,008 (205)

Monoamine Oxidase-Inhibiting Antidepressants: A Clinical Update

Psychiatric Clinics of North America, 1984
This article outlines the latest information on the clinical efficacy of MAOIs and provides the physician with guidelines for their safe use. The important side effects of this class of drugs are also summarized along with an up-to-date account of their possible molecular mechanism of action.
D L, Murphy, T, Sunderland, R M, Cohen
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A discontinuous luminometric assay for monoamine oxidase

Biochemical Pharmacology, 1993
A simple, sensitive and convenient discontinuous luminometric assay for monoamine oxidase (MAO) is described. It is based on measurement of the light production from the peroxidase-catalysed chemiluminescent oxidation of 5-amino-2,3-dihydro-1,4-phthalazinedione (luminol) by the hydrogen peroxide produced in the MAO reaction.
E M, O'Brien, K A, Kiely, K F, Tipton
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A radiochemical method for monoamine oxidase assay

Analytical Biochemistry, 1969
Abstract A simple radiochemical method is described for the assay of monoamine oxidase utilizing tritiated tyramine. The synthesis of tyramine-1,2-3H from tyrosine-2,3-3H is reported. Tritium, released by the oxidation of tyramine-1,2-3H by monoamine oxidase, was counted by conventional liquid scintillation techniques.
J H, Fellman, E S, Roth, R F, Mollica
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A bioluminescent assay for monoamine oxidase activity

Analytical Biochemistry, 2006
This article describes a novel two-step homogeneous bioluminescent assay for monoamine oxidase (MAO) that is simple, sensitive, and amenable to high-throughput screening. In the first step, MAO reacts with an aminopropylether analog of methyl ester luciferin.
Michael P, Valley, Wenhui, Zhou, Erika M, Hawkins, John, Shultz, James J, Cali, Tracy, Worzella, Laurent, Bernad, Troy, Good, Dave, Good, Terry L, Riss, Dieter H, Klaubert, Keith V, Wood   +11 more
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A clinical overview of monoamine oxidase inhibitors

Psychosomatics, 1985
Abstract After examining reasons for the revival of interest in use of the monoamineoxidase inhibitors (MAOIs), the author evaluates current thinking and experience concerning patient selection and indications, dosage, side effects, drug interactions, combination with tricyclic antidepressants (TCAs), and instructions for the patient.
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A sensitive fluorometric assay for monoamine oxidase

Analytical Biochemistry, 1969
Abstract A rapid and convenient fluorometric assay for monoamine oxidase is reported, based on the oxidation of homovanillic acid to a highly fluorescent compound by the hydrogen peroxide produced in the reaction. The principal advantages of the method over those currently available are its simplicity, its high sensitivity, and the fact that it does ...
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Monoamine oxidase A and B: A useful concept?

Biochemical Pharmacology, 1978
The use of a number of inhibitors of monoamine oxidasc (monoamine:O, oxidoreductase, EC 1.4.3.4) has shown that many mam~lian tissues contain two major forms of the enzymic activity that differ in their substrate specificities and sensitivities to inhibitors.
Christopher J. Fowler, Brian A. Callingham, Timothy J. Mantle, Keith F. Tipton   +3 more
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TRANYLCYPROMINE (PARNATE) A NEW MONOAMINE OXIDASE INHIBITOR

American Journal of Psychiatry, 1960
Preliminary clinical experience indicates that tranylcypromine (Parnate) is an improved type of monoamine oxidase inhibitor that appears to be more rapid in its action, effective in smaller doses (1 to 3 tablets a day–usually one tablet b. i. d.) and relatively free of side effects.
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Localization of distinct monoamine oxidase a and monoamine oxidase b cell populations in human brainstem

Neuroscience, 1988
Monoclonal antibodies, specific for either monoamine oxidases A or B, were used to determine the localization of monoamine oxidase in the human brain. Two distinct populations of neurons were detected by immunocytochemical staining. Neurons in regions rich in catecholamines were positive for monoamine oxidase A, including the nucleus locus coeruleus ...
K N, Westlund, R M, Denney, R M, Rose, C W, Abell   +3 more
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-Octopamine as a substrate for monoamine oxidase

Life Sciences, 1979
Abstract m -Octopamine was characterized as substrate for monoamine oxidase (MAO) in rat brain and liver mitochondria. The K m and V max values of the brain enzyme were 735 μM and 32.5 nmoles/mg protein/30 min, and those of the liver enzyme 351 μM and 125 nmoles/mg protein/30 min, respectively.
O, Suzuki, H, Hattori, Y, Katsumata, M, Oya   +3 more
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