Results 191 to 200 of about 49,705 (278)

Cytokine Dynamics in Bortezomib‐Induced Peripheral Neuropathy: Challenges in Translating Preclinical Findings to Humans

Journal of the Peripheral Nervous System, Volume 31, Issue 1, March 2026.
ABSTRACT Background and Aims Bortezomib‐induced peripheral neuropathy (BIPN) remains a common treatment side effect in patients with multiple myeloma (MM). Data from rodent models indicate a role of proinflammatory cytokines in BIPN pathophysiology, making them potential therapeutic targets.
Nadine Cebulla, Daniel Schirmer, Eva Runau, Leon Flamm, Calvin Terhorst, Laura Jähnel, Johanna Güse, Nicola Giordani, Annett Wieser, Felicitas Schoch, Marie‐Luise Reinle, Sonja Gommersbach, Aikaterini Papagianni, Xiang Zhou, Hermann Einsele, Ann‐Kristin Reinhold, Heike Rittner, K. Martin Kortüm, Claudia Sommer   +18 more
wiley   +1 more source

Inequalities in availability of clinical trials for pediatric, adolescent, and young adult patients with cancer in Europe: results from the SIOPE OCEAN project. [PDF]

Lancet Reg Health Eur
Rauwolf KK, de Rojas T, Martins M, Otth M, Dirksen U, Heenen D, Kameric L, Kearns P, Ladenstein R, Owens C, Queiroz C, Sullivan R, Rizzari C, Vassal G, European Society for Paediatric Oncology (SIOPE).   +14 more
europepmc   +1 more source

Serum Neurofilament Light Chain and Glial Fibrillary Acidic Protein as Biomarkers in Hereditary Transthyretin Amyloidosis Polyneuropathy

Journal of the Peripheral Nervous System, Volume 31, Issue 1, March 2026.
ABSTRACT Background and Aims In individuals with hereditary transthyretin amyloidosis (ATTRv) polyneuropathy, monitoring of disease progression and treatment response is crucial. The objective is to determine if serum neurofilament light chain (sNfL) and serum glial fibrillary acidic protein (sGFAP) are reliable biomarkers of ATTRv polyneuropathy ...
Valentin Loser, Pascal Benkert, Alex Vicino, Nicolas Ghika, Pansy Lim Dubois Ferrière, Chantal Daigneault, Thierry Kuntzer, Aleksandra Maleska Maceski, Jens Kuhle, Marie Théaudin   +9 more
wiley   +1 more source

Letter to the Editor: Severity of elbow mobility limitation in pediatric patients with a displaced supracondylar humerus fracture requiring surgical treatment-A monocentric retrospective clinical study. [PDF]

J Child Orthop
Rehm A, Lawrence JE, Osman H, Worley RJ, Morriss F, Liew I.   +5 more
europepmc   +1 more source

Understanding Nurses' and Physicians' Knowledge, Use and Perspectives on Nitrous Oxide/Oxygen Use in Paediatrics: A Cross‐Sectional Study

Nursing in Critical Care, Volume 31, Issue 2, March 2026.
ABSTRACT Background Nitrous oxide/oxygen (N2O/O2 50%/50%) is an effective and safe technique for procedural sedation in paediatric settings; however, the knowledge, use and perspectives of healthcare professionals regarding N2O/O2 remain limited. Aim To investigate the knowledge, use and perspectives of healthcare professionals regarding N2O/O2 in ...
Valentina Simonetti, Beatrice Gullo, Ilenia Stracci, Davide Miniscalco, Elisa Capriotti, Silvia Oroli, Michela Arragoni, Lamberto Manzoli, Giancarlo Cicolini, Dania Comparcini   +9 more
wiley   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, Volume 13, Issue 2, Page 310-323, February 2026.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

Reversible impairment of non-invasively assessed mitochondrial oxygen metabolism in the long-term course of patients with sepsis: a prospective monocentric cohort study. [PDF]

Intensive Care Med Exp
Standke A, Neu C, Baumbach P, Plooij AK, Skitek K, Götze J, Coldewey SM.   +6 more
europepmc   +1 more source

Analysis of Patients With Monocytic and Monocytic‐Like Acute Myeloid Leukemia, Including AML‐M4 and AML‐M5, Treated With Venetoclax Plus Azacitidine

American Journal of Hematology, Volume 101, Issue 3, Page 577-580, March 2026.
Marina Konopleva, Courtney D. DiNardo, Yan Sun, Paul Jung, Sanam Loghavi, Jalaja Potluri, Monique Dail, Brenda Chyla, Daniel A. Pollyea   +8 more
wiley   +1 more source

Fluorescence indocyanine green (ICG) for sentinel-lymph-node mapping in colorectal cancer: a systematic review. [PDF]

Langenbecks Arch Surg
Litchinko A, Meyer J, Buhler L, Ris F, Adamina M.   +4 more
europepmc   +1 more source

A set of serum proteomic biomarkers differentiates celiac children from age and human leukocyte antigen‐matched healthy controls

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 2, Page 508-515, February 2026.
Abstract Objective The latest European Society of Gastroenterology Hepatology and Nutrition (ESPGHAN) criteria for celiac disease (CD) diagnosis reduced the requirement for a small intestinal biopsy but still, for most of the cases a small intestinal biopsy is required for a safe diagnosis: hence the attempt to identify serum biomarkers that could ...
Roberta Mandile, Michele Francesco di Tolla, Martina Carpinelli, Janneke Nicoline Samsom, Rossella De Cegli, Maria Vittoria Barone, Riccardo Troncone, Pietro Formisano, Luigi Greco, Renata Auricchio   +9 more
wiley   +1 more source