Results 301 to 310 of about 759,957 (341)
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Monoclonal antibodies to prothrombin
Thrombosis Research, 1987Hybridoma technology was used for the production of murine monoclonal antibodies to bovine normal prothrombin. Hybrid cell cultures were assayed for the production of antibodies, both in the absence and presence of calcium ions, by Enzyme-Linked Immunosorbent Assay (ELISA). Antibody-producing cell lines were cloned two times and grown as ascites tumors.
Oscar Sudilovsky, Om P. Malhotra
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Monoclonal antibodies in oncology
Radiotherapy and Oncology, 1986Monoclonal antibodies (MCAs) can be used to differentiate between normal and neoplastic cells and thus exploited for diagnostic and, ultimately, therapeutic gain. The evidence for the existence of human tumour antigens is reviewed. Several areas of diagnosis are already benefiting from the application of the monoclonal technology.
Stephen Chan, Karol Sikora
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Deimmunization of Monoclonal Antibodies
2008Immunogenicity is a major limitation to therapy with certain monoclonal antibodies and proteins. A major driver for immunogenicity is the presence of human T-cell epitopes within the protein sequence which can activate helper T-cells resulting in the sustained production of antibodies and neutralization of the therapeutic effect.
Laura J. Crompton +3 more
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Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies
Ca-A Cancer Journal for Clinicians, 2022Javier Cortés +2 more
exaly
Current treatment and future directions in the management of anal cancer
Ca-A Cancer Journal for Clinicians, 2022Leila T Tchelebi +2 more
exaly
Modern developments in germline pharmacogenomics for oncology prescribing
Ca-A Cancer Journal for Clinicians, 2022Natalie M Reizine, Peter H O'donnell
exaly
Monoclonal Antibody TfR Monoclonal Antibody
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 2017openaire +2 more sources