Results 211 to 220 of about 90,200,282 (296)

Anti‐Inflammatory Effects of Punicic Acid and Its Molecular Mechanisms in RAW264.7 Cells and Zebrafish

Food Safety and Health, EarlyView.
Punicic acid (PA) was enriched and purified from PSO by molecular distillation with significant anti‐inflammatory activity to RAW264.7 cells, as well as to zebrafish. Anti‐inflammatory mechanism involved regulating NF‐κB and MAPK signaling pathways. ABSTRACT Punicic acid (PA) is the main fatty acid in pomegranate seeds, which shows multiple biological ...
Mengqi Zhang, Caiyun Feng, Mengyao Zhu, Xu Guo, Yingying Chen, Wenwen Hu, Fei Dong, Jinyue Sun, Chao Liu   +8 more
wiley   +1 more source

Safety and Metabolic Effects of Withania somnifera Seed Extract and Powder in Rats: Insights From DPP‐4 Molecular Docking

Food Safety and Health, EarlyView.
Withania somnifera seed extract and powder improved metabolic parameters in rats, particularly at higher extract doses, without evident hepatic, renal, hematological, or histopathological toxicity. Molecular docking further predicted strong DPP‐4 inhibitory potential of withanone, supporting the antidiabetic potential of W. somnifera seeds.
Muhammad Usman Khalid, Muhammad Waqar, Muhammad Tauseef Sultan, Muhammad Maaz, Ahmad Mujtaba Noman, Hassan Raza, Muhammad Israr, Djilali Benabdelmoumene, Abdifetah Ibrahim Omar   +8 more
wiley   +1 more source

Monocyte-to-lymphocyte ratio as an inflammatory biomarker for predicting diabetic peripheral neuropathy in type 2 diabetes mellitus patients. [PDF]

BMC Endocr Disord
Li J, Hu F, Lu X, Shen Y, Chen J, Zhang H.   +5 more
europepmc   +1 more source

Monocyte-to-lymphocyte ratio as a predictive marker for breast cancer treatment outcomes: a narrative review. [PDF]

Ann Med Surg (Lond)
Obeagu EI.
europepmc   +1 more source

Gene signatures characterizing driver mutations in lung squamous carcinoma are predictive of the progression of pre‐cancer lesions

International Journal of Cancer, EarlyView.
What's New? Lung squamous cell carcinoma (LUSC) is more aggressive than lung adenocarcinoma, and is most often diagnosed at an advanced stage. Here, the authors evaluated gene expression data from LUSC tumors and came up with gene signatures for 34 genetic abnormalities whose expression changes throughout different precancerous stages. Several of these
Yupei Lin, Venugopalareddy Mekala, Jianrong Li, Xiang Wang, Muhammad Aminu, Jia Wu, Jianjun Zhang, Robert Taylor Ripley, Christopher I. Amos, Chao Cheng   +9 more
wiley   +1 more source

Association between the monocyte-to-lymphocyte ratio and 28-day all-cause mortality in sepsis-associated delirium patients: a retrospective study and machine learning. [PDF]

BMC Infect Dis
Zhao Y, Jiang J, Pu J, Yang J, Na A, Ding J, Lu Q, Yang K, Zhu H.   +8 more
europepmc   +1 more source

Evaluating the diagnostic value of PLR and related hematologic parameters combined with CA‐125 for endometriomas

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Endometriosis is a chronic inflammatory disease, with inflammation relating to pathogenesis and staging. We compared inflammatory indices and clinical characteristics between patients with ovarian endometriomas and those with benign ovarian tumors to evaluate their diagnostic value and identify affordable blood markers for diagnosis ...
Pingping Su, Yanni Huang, Fenhong Kang, Lili Zhang, Lirui Yu, Hongli Liu   +5 more
wiley   +1 more source

Novel prognostic score based on the monocyte-to-lymphocyte ratio and CAVE score for epilepsy after primary intracerebral hemorrhage. [PDF]

BMC Neurol
He W, Xu M, Lin R, Wang S, Huang W, Chen H, Yang Y, Lin J.   +7 more
europepmc   +1 more source

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

iMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu, Xiaoyan Chen, Zichang Chen, Yalun Liang, Gokhan Zengin, Qian Zhang, Wenlong Sun, Meng‐Yao Li   +7 more
wiley   +1 more source

Euthyroid Sick Syndrome (ESS) and Monocyte-to-Lymphocyte Ratio (MLR) Are Predictors of Complications in Geriatric Hip Fractures: A Single-Center Retrospective Analysis. [PDF]

J Clin Med
Capece G, Di Costa D, Pesare E, Pomponi M, Maccauro V, Comodo RM, Kaplan R, Capece U, Farsetti P, Covino M, Maccauro G, Vitiello R.   +11 more
europepmc   +1 more source