Background: Sepsis is characterised by multi-organ failure due to an uncontrolled immune response to infection. Sepsis prevalence is increased in developing countries and requires prompt diagnosis and treatment.
Jason van Rensburg +3 more
doaj +1 more source
Monocytes regulate the mechanism of T-cell death by inducing Fas-mediated apoptosis during bacterial infection. [PDF]
Monocytes and T-cells are critical to the host response to acute bacterial infection but monocytes are primarily viewed as amplifying the inflammatory signal.
A Kadioglu +64 more
core +4 more sources
Evaluation of monocyte-to-high-density lipoprotein cholesterol ratio and monocyte-to-lymphocyte ratio in ischemic stroke [PDF]
Objectives We aimed to evaluate the diagnostic value of the combination of the monocyte-to-high-density lipoprotein cholesterol ratio (MHR) with the monocyte-to-lymphocyte ratio (MLR) in ischemic stroke patients. Methods There were 253 patients who were diagnosed with ischemic stroke and 211 healthy subjects enrolled into this retrospective study ...
Huiling Liu, Feng Zhan, Yazhou Wang
openaire +3 more sources
Tumor-induced senescent T cells promote the secretion of pro-inflammatory cytokines and angiogenic factors by human monocytes/macrophages through a mechanism that involves Tim-3 and CD40L [PDF]
Solid tumors are infiltrated by immune cells where macrophages and senescent T cells are highly represented. Within the tumor microenvironment, a cross-talk between the infiltrating cells may occur conditioning the characteristic of the in situ immune ...
Acosta Rodriguez, Eva Virginia +8 more
core +2 more sources
Value of the Ratio of Monocytes to Lymphocytes for Monitoring Tuberculosis Therapy
Objective. The objective of this study was to evaluate the change of the ratio of monocytes to lymphocytes in patients with active tuberculosis, such as to provide reference for clinical diagnosis and treatment.Methods. All data were collected from the clinical database of The Fifth People’s Hospital of Taiyuan, China.
Wei Wang +5 more
openaire +3 more sources
VEGF(164)-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization [PDF]
Hypoxia-induced VEGF governs both physiological retinal vascular development and pathological retinal neovascularization. In the current paper, the mechanisms of physiological and pathological neovascularization are compared and contrasted.
Adamis, AP +14 more
core +1 more source
The prognostic value of lymphocyte-to-monocyte ratio in retinopathy of prematurity [PDF]
AIM: To evaluate the associations between development of retinopathy of prematurity (ROP) and serum lymphocyte-to-monocyte ratio (LMR), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR).
Yu-Xiang Hu +8 more
doaj +1 more source
Homocysteine and Peripheral White Blood Cell Count-derived Ratios: Insights from Healthy Population
Background: Homocysteine (Hcy) and dyslipidemia are established risk parameters of atherosclerosis. Considerable research has been conducted using ratios of lymphocytes to other cellular components of the peripheral white blood cell count (PBC) as ...
Pawar Neelam +3 more
doaj +1 more source
The immune response crucially determines the survival of patients with malignant tumors including breast carcinoma. The aim of the present study was to evaluate retrospectively an association of peripheral blood cell count (PBC)-derived ratios and ...
Melichar Bohuslav +10 more
doaj +1 more source
ObjectiveTo examine the utility of the peripheral blood neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) as biomarkers of prognosis in seropositive autoimmune encephalitis (AE).MethodsIn this multicenter study, we ...
James Broadley +29 more
doaj +1 more source

