Results 51 to 60 of about 2,735 (209)

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Peripheral Immune Cell Ratios and Clinical Outcomes in Seropositive Autoimmune Encephalitis: A Study by the Australian Autoimmune Encephalitis Consortium

Frontiers in Immunology, 2021
ObjectiveTo examine the utility of the peripheral blood neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) as biomarkers of prognosis in seropositive autoimmune encephalitis (AE).MethodsIn this multicenter study, we ...
James Broadley, James Broadley, Robb Wesselingh, Robb Wesselingh, Udaya Seneviratne, Udaya Seneviratne, Udaya Seneviratne, Chris Kyndt, Chris Kyndt, Paul Beech, Paul Beech, Katherine Buzzard, Katherine Buzzard, Cassie Nesbitt, Cassie Nesbitt, Wendyl D’Souza, Wendyl D’Souza, Amy Brodtmann, Amy Brodtmann, Tomas Kalincik, Tomas Kalincik, Helmut Butzkueven, Helmut Butzkueven, Terence J. O’Brien, Terence J. O’Brien, Mastura Monif, Mastura Monif, Mastura Monif, Mastura Monif, Australian Autoimmune Encephalitis Consortium   +29 more
doaj   +1 more source

Neutrophil to lymphocyte ratio, Monocyte to lymphocyte ratio, platelet to lymphocyte ratio in different etiological causes of thyrotoxicosis

TURKISH JOURNAL OF MEDICAL SCIENCES, 2019
The most common causes of thyrotoxicosis include Graves’ disease (GD), toxic multinodular goiter (TMNG), toxic adenoma (TA), and subacute granulomatous thyroiditis (SAT). In our study, we aimed to see whether neutrophil‐to‐lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet‐to‐lymphocyte ratio (PLR), and mean platelet volume (MPV) may ...
TAŞKALDIRAN, Işılay, OMMA, Tülay, ÖNDER, Çağatay Emir, FIRAT, Sevde Nur, KOÇ, Gönül, KILIÇ, Mustafa Kemal, KUŞKONMAZ, Şerife Mehlika, ÇULHA, Cavit   +7 more
openaire   +2 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Evaluation of Monocyte/Lymphocyte, Neutrophil/Lymphocyte, and Platelet/Lymphocyte Ratios in Patients with Temporal Lobe Epilepsy

Archives of Epilepsy, 2022
Objective:This study aimed to determine the levels of monocyte/lymphocyte, neutrophil/lymphocyte, and platelet/lymphocyte (PLR) ratios in patients with mesial temporal lobe epilepsy, which is considered to be a chronic inflammatory brain disease, by ...
Aslı Bolayır
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Diagnostic Value of Inflammatory Factors in Pathology of Bladder Cancer Patients

Frontiers in Molecular Biosciences, 2020
We conducted this study to evaluate the diagnostic value of Inflammatory Factors (IFs) in the pathology of bladder cancer patients. The patients who were diagnosed with urothelial bladder carcinoma (bladder cancer) and underwent surgical treatment in our
Xingxing Tang, Yudong Cao, Jia Liu, Shuo Wang, Yong Yang, Peng Du   +5 more
doaj   +1 more source

Neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and monocyte-to-lymphocyte ratio in depressed patients with suicidal behavior: A systematic review

European Psychiatry, 2023
Abstract Background Inflammatory biomarkers are reportedly increased in depressed patients. Several studies have been conducted using neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and monocyte/lymphocyte ratio (MLR).
A Velasco, A Lengvenyte, J Rodriguez-Revuelta, L Jimenez-Treviño, P Courtet, MP Garcia-Portilla, J Bobes, PA Sáiz   +7 more
openaire   +6 more sources

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source