Results 371 to 380 of about 712,808 (414)

Monocyte CCL2 signaling possibly contributes to increased asthma susceptibility in type 2 diabetes. [PDF]

Sci Rep
Luo T, Guo W, Ji W, Du W, Lv Y, Feng Z.
europepmc   +1 more source

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

Advanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua, Limin Kong, Li Fan, Yanan Bai, Yujun Zhou, Yanfang Zhang, Qingwei Zhao, Xiaoyang Lu, Hongyu Yang, Hangyang Li, Peili Ding, Yuyu Nan, Qinghua Ji, Ping Yang, Lu Li, Yijing Xin, Lijuan Zhao, Wei Yang, Wenqiao Yu, Saiping Jiang   +19 more
wiley   +1 more source

Predictive value of the monocyte count for determining the risk of postoperative moderate-to-severe ARDS in patients undergoing one-lung ventilation during radical treatment of esophageal cancer. [PDF]

Front Med (Lausanne)
Zhang F, Lu S, Wang G, Xu H, Huang D, Li X.   +5 more
europepmc   +1 more source

CCN1 Enhances Tumor Immunosuppression through Collagen‐Mediated Chemokine Secretion in Pancreatic Cancer

Advanced Science, EarlyView.
CCN1 modulates the tumor microenvironment in pancreatic cancer by promoting collagen‐dependent chemokine production, thereby facilitating immune evasion. Deletion of CCN1 not only suppresses tumor growth but also enhances immune cell infiltration and increases tumor sensitivity to both chemotherapy and immunotherapy.
Hongjie Fan, Huzi Zhao, Lili Gao, Yucheng Dong, Pei Zhang, Pengfei Yu, Yunfei Ji, Zhe‐Sheng Chen, Xinmiao Liang, Yang Chen   +9 more
wiley   +1 more source

Association between the (neutrophil + monocyte)/albumin ratio and all-cause mortality in sepsis patients: a retrospective cohort study and predictive model establishment according to machine learning. [PDF]

BMC Infect Dis
Liu L, Ma Q, Yu G, Ji X, He H.
europepmc   +1 more source

Sustained release of cytokines from migrasomes. [PDF]

Extracell Vesicles Circ Nucl Acids
Zhen Y, Stenmark H.
europepmc   +1 more source

Immune-Infiltrated Cancer Spheroid Model with Vascular Recirculation Reveals Temporally Dependent and Tissue-Specific Macrophage Recruitment. [PDF]

Adv Healthc Mater
Zhang F, Jozani KA, Chakravarty A, Lin D, Hollinger A, Rajasekar S, Zhang B.   +6 more
europepmc   +1 more source

Longitudinal CNS and systemic T-lymphocyte and monocyte activation before and after antiretroviral therapy beginning in primary HIV infection. [PDF]

Front Immunol
Chan P, Li X, Li F, Emu B, Price RW, Spudich S.   +5 more
europepmc   +1 more source

<i>Bordetella</i> adenylate cyclase toxin elicits chromatin remodeling and transcriptional reprogramming that blocks differentiation of monocytes into macrophages. [PDF]

mBio
Ahmad JN, Modrak M, Fajfrova M, Sotoca BM-B, Benada O, Sebo P.   +5 more
europepmc   +1 more source

An In-Silico Study to Identify Relevant Biomarkers in Sepsis Applying Integrated Bulk RNA Sequencing and Single-Cell RNA Sequencing Analyses. [PDF]

Glob Chall
Ye Q, Dong Y, Liang J, Lv J, Tang R, Zhao S, Hou G.   +6 more
europepmc   +1 more source