Results 201 to 210 of about 47,631 (258)

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

The Genetics of Hidradenitis Suppurativa. [PDF]

Clin Cosmet Investig Dermatol
Gupta AK, Dennis DJ, Economopoulos V, Magalhaes RF, Saunte DML, Piguet V.   +5 more
europepmc   +1 more source

Microarray Gene Expression Analysis of Lesional Skin in Canine Vesicular Cutaneous Lupus Erythematosus (VCLE)

Veterinary Dermatology, EarlyView.
Background: Vesicular cutaneous lupus erythematosus (VCLE) is a rare autoimmune disease in dogs and is considered the canine counterpart of human subacute cutaneous lupus erythematosus (SCLE). However, the molecular mechanisms underlying VCLE remain incompletely defined.
Treasa Clifford, Lauren W. Stranahan, Dominique J. Wiener, M. Kelly Keating, Renato Leon, Frane Banovic   +5 more
wiley   +1 more source

Mechanical sensitization of sensory afferents after passive transfer of fibromyalgia IgG

The Journal of Physiology, EarlyView.
Abstract figure legend In addition to widespread pain and fatigue, people with fibromyalgia (FM) experience sensory abnormalities and report lingering, painful sensations after touch or mechanical probing of the skin. Administration of IgG purified from FM patients to mice transfers symptoms and signs of FM.
Mathilde R. Israel, Nisha Vastani, Clive Gentry, Andreas Goebel, Stuart Bevan, David A. Andersson   +5 more
wiley   +1 more source

Clinical features and prognostic analysis of very early-onset inflammatory bowel disease. [PDF]

BMC Pediatr
Gong Y, He X, Zhong X.
europepmc   +1 more source

Genetic and phenotypic landscape of monogenic lupus: insights from an international cohort. [PDF]

Lupus Sci Med
Al-Mayouf SM, Ziaee V, Movahedi N, Kostik M, Alhuthil R, Alsonbul A, Asiri A, Volpi S, Gattorno M, Majeed M, Al Abrawi S, Yateem M, Alharthi A, Al-Saoud S, Alazami AM, AlSaleem A.   +15 more
europepmc   +1 more source

Monogenic lupus with SLC7A7 mutations: a retrospective study from a Chinese center. [PDF]

Orphanet J Rare Dis
Li Y, Lv Q, Lu W, Liu H, Feng J, Guan W, Gong Y, Zeng Q, Zhang X, Xu H, Sun L.   +10 more
europepmc   +1 more source

The Genetic Landscape of Diabetes Mellitus: Lessons from Monogenic and Polygenic Forms. [PDF]

Life (Basel)
Nilo D, Nilo R, Sircana MC, Sasso FC, Acierno C, Bonfrate L, Caturano A.   +6 more
europepmc   +1 more source

Low-level mosaic variants causing the pancreatic disease congenital hyperinsulinism can be detected from blood DNA. [PDF]

EBioMedicine
Bennett JJ, Laver TW, Männistö JME, Houghton JAL, De Franco E, Kalyon O, Wright S, Johnson AM, De Leon DD, Globa E, Kummer S, Banerjee I, Dastamani A, International Congenital Hyperinsulinism Consortium, Wakeling MN, Johnson MB, Flanagan SE.   +16 more
europepmc   +1 more source

Validation of Parkinson's Disease Diagnoses in a National Register: Accuracy, Limitations, and Utility. [PDF]

Clin Epidemiol
Räty V, Kuusimäki T, Vahlberg T, Tolppanen AM, Kaasinen V.   +4 more
europepmc   +1 more source