Results 41 to 50 of about 565,946 (269)
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Formation and removal of alkylthiolate self-assembled monolayers on gold in aqueous solutions [PDF]
, 2006 We report the development of novel reagents and approaches for generating recyclable biosensors. The use of aqueous media for the formation of protein binding alkylthiolate monolayers on Au surfaces results in accelerated alkylthiolate monolayer ...
Canaria, Christie A. +7 more
core +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Collapse Mechanisms of Nascent and Aged Sea Spray Aerosol Proxy Films
Atmosphere, 2018 Sea spray aerosol (SSA) is highly enriched in marine-derived organic compounds during seasons of high biological productivity, and saturated fatty acids comprise one of the most abundant classes of molecules.
Kimberly A. Carter-Fenk +1 more
doaj +1 more source
X-ray fluorescence spectroscopy from ions at charged vapor/water interfaces
, 2009 X-ray fluorescence spectra from monovalent ions (Cs+) that accumulate from dilute solutions to form an ion-rich layer near a charged Langmuir monolayer are presented.
Bu, Wei, Vaknin, David
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Monolayers of fatty acids. I. Stearic acid on aqueous solutions of ethanol
Grasas y Aceites, 1991 The structure and stability of fatty acid monolayers spread on aqueous solutions with ethanol has been studied. The experiments were carried out isothermically using a commercial Langmuir balance (Lauda).
J. M. Rodríguez Patino +2 more
doaj +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Formation of a large-area monolayer of polystyrene film via the spin-coating method [PDF]
Nuclear Technology and Radiation Protection, 2018 The self-assembly methods, an inexpensive and high throughput technique capable of producing nanostructure arrays, relies on the formation on a monolayer of self-assembled nanospheres.
Modrić-Šahbazović Almedina H. +5 more
doaj +1 more source