Results 51 to 60 of about 565,946 (269)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Drugs and Drug CandidatesThe monolayer (two-dimensional or 2D) cell culture, while widely used, lacks fidelity in replicating vital cell interactions seen in vivo, leading to a shift toward three-dimensional (3D) models.
Anali del Milagro Bernabe Garnique +5 more
doaj +1 more source
Molecules, 2020 In this examination, we investigated the effect of lipoic acid (LA) on the properties of biological membrane models (monolayers, bilayers, and liposomes) formed from phosphatidylcholine (PC) or phosphatidylserine (PS) using the Langmuir ...
Paulina Laszuk +2 more
doaj +1 more source
Premade Nanoparticle Films for the Synthesis of Vertically Aligned Carbon Nanotubes
C, 2021 Carbon nanotubes (CNTs) offer unique properties that have the potential to address multiple issues in industry and material sciences. Although many synthesis methods have been developed, it remains difficult to control CNT characteristics. Here, with the
Abdul Hoque +3 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
A Novel Strategy for Fabricating a Strong Nanoparticle Monolayer and Its Enhanced Mechanism
Nanomaterials, 2019 This work presents the preparation of cross-linking Au nanoparticle (NP) monolayer membranes by the thiol exchange reaction and their enhanced mechanical properties.
Jun Zhou +4 more
doaj +1 more source
Improved Contact Resistance by a Single Atomic Layer Tunneling Effect in WS2/MoTe2 Heterostructures
Advanced Science, 2021 Manipulation of Ohmic contacts in 2D transition metal dichalcogenides for enhancing the transport properties and enabling its application as a practical device has been a long‐sought goal.
Jihoon Kim +5 more
doaj +1 more source
Energies, 2021 A piezoelectric sensor is a typical self-powered sensor. With the advantages of a high sensitivity, high frequency band, high signal-to-noise ratio, simple structure, light weight, and reliable operation, it has gradually been applied to the field of ...
Quan Wang +4 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Methane-Mediated Vapor Transport Growth of Monolayer WSe2 Crystals
Nanomaterials, 2019 The electrical and optical properties of semiconducting transition metal dichalcogenides (TMDs) can be tuned by controlling their composition and the number of layers they have.
Hyeon-Sik Jang +7 more
doaj +1 more source