Results 61 to 70 of about 239,484 (302)
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Azobenzenes and dithiocarbamates in molecular film devices [PDF]
The “top-down” approach to improve the performance of small electronic devices is becoming more and more challenging due to economic and engineering restrictions. Thus, researchers seek for alternatives towards efficient, smaller and faster devices. The “
Reinders, Federica
core +1 more source
Mechanoresponse of curved epithelial monolayers lining bowl-shaped 3D microwells [PDF]
peer reviewedThe optimal functioning of many organs relies on the curved architecture of their epithelial tissues [1]. However, the mechanoresponse of epithelia to changes in curvature remains misunderstood.
Versaevel, Marie +3 more
core +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Monolayers of linear saturated succinate polyesters at air-liquid interfaces
The surface pressure-area isotherms at 25C are reported for some linear saturated polyesters spread as monolayers at air-aqueous interfaces. Monolayers of poly(ethylene succinate), poly(pentamethylene succinate), and poly(neopentyl succinate) were ...
Lee, Wendell M.; Shereshefsky, J. Leon; Stromberg, Robert R.
core +1 more source
An extracellular matrix protein, fibronectin (Fn), was covalently immobilized on 316L stainless steel, L605 cobalt chromium (CoCr), and nickel titanium (NiTi) surfaces through an 11-mercaptoundecanoic acid (MUA) self-assembled monolayer (SAM) pre-formed ...
Hesam Dadafarin +4 more
doaj +1 more source
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
From self assembled monolayers to clickable gold nanoparticles [PDF]
The aim of the present PhD thesis was the investigation of the behavior of gold nanoparticle stabilizing oligo thioether ligands on gold surfaces and further on to develop a protocol for the directed assembly of mono functionalized gold nanoparticle into
Sander, Fabian
core +1 more source
Gold Nanoparticles Monolayer Based Field‐Effect Molecular Sensors
The rapid and efficient sensing mechanism of molecules and bimolecular species is crucial for healthcare, biomedical, and safety applications. Such sensors need to be robust and able to measure low concentrations of molecular species.
Yawar Abbas +5 more
doaj +1 more source
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source

