Results 211 to 220 of about 59,085 (291)

Repurposing Hetrombopag for Multiple Myeloma by Targeting PNPO: A Celastrol‐Inspired Approach

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 5, May 2026.
Hetrombopag targeted PNPO to inhibit multiple myeloma. ABSTRACT Multiple myeloma (MM) is a malignancy of plasma cells whose excessive immunoglobulin production elevates reactive oxygen species (ROS), promoting pathogenesis. Active compounds from Traditional Chinese Medicine, such as celastrol, can exert antitumour effects by further increasing ROS ...
Tianyi Yu, Cheng Wang, Jingru Xie, Yongxin Wei, Hongwei Cui, Huaxia Zhang, Fan Zhou, Zhendong Deng, Ye Yang, Chunyan Gu   +9 more
wiley   +1 more source

Developing Heterogeneous Porous 3D-Printed SiO₂-Pd-K₂SiO₃ Monolithic Catalyst via Surface MOF Growth and Pyrolysis for the Synthesis of Antitumoral Isatins. [PDF]

Pharmaceutics
Druta A, Bouhmala R, Ragdi T, Luna M, Bañobre-López M, Masaguer CF, Amorín M, Barbosa S, Taboada P, Coelho A.   +9 more
europepmc   +1 more source

Far, Moderate or in Between? The Ties That Shape Canadian Right‐Wing Youth Activism

Canadian Review of Sociology/Revue canadienne de sociologie, Volume 63, Issue 2, May 2026.
ABSTRACT Canadian right‐wing youth social movement actors are not a monolith. In this paper, I analyze 45 interviews and notes from a year of ethnographic fieldwork with a population of Canadian right‐wing youth activists between 2023 and 2024. While these youth activists are part of the same right‐wing organizations, some espouse far‐right ideas ...
Kayla Preston
wiley   +1 more source

Self-Supported Branched Poly(ethylenimine) Monoliths from Inverse Template 3D Printing for Direct Air Capture. [PDF]

ACS Appl Mater Interfaces
Narayanan P, Kim SY, Alhazmi D, Jones CW, Lively RP.   +4 more
europepmc   +1 more source

SARS‐CoV‐2 nucleocapsid protein variants have differential RNA chaperone activity

The FEBS Journal, Volume 293, Issue 9, Page 2579-2598, May 2026.
The SARS‐CoV‐2 nucleocapsid (N) protein is not only the specific viral RNA packaging protein, but also acts as an RNA chaperone, facilitating RNA folding. We show that it facilitates RNA annealing through its RBD–IDR2–CTD region, identifying it as a functional RNA chaperone.
Sabrina Babl, Julia M. Seidel, Fabian Kugler, Elisabeth Silberhorn, Anna Ludwig, Jonas Abel, Sophia Winklbauer, Niklas Schaub, Silvia Materna‐Reichelt, Kamran Honarnejad, Nataša Stojanović Gužvić, Gernot Längst   +11 more
wiley   +1 more source

Melamine-Based Molecularly Imprinted Monoliths Targeting Glyphosate in Aqueous Media: Synthesis and Binding Mechanism Elucidation. [PDF]

ACS Omega
Huynh CM, Luong NT, Nguyen T, Dinh NP, Boily JF, Irgum K.   +5 more
europepmc   +1 more source

Scoping Review of Sexual and Gender Minority Health Research in Ireland

Journal of Advanced Nursing, Volume 82, Issue 5, Page 4625-4659, May 2026.
ABSTRACT Aim To map existing sexual and gender minority (SGM) health research in Ireland, identify gaps in literature and outline priorities for future research and healthcare. SGM is an umbrella term that includes people who identify as lesbian, gay, bisexual, transgender, queer or intersex and is sometimes abbreviated as LGBTQI+.
John P. Gilmore, Tonda L. Hughes, Sean Kearns, Laurie A. Drabble, Diarmuid Stokes, Siobhán D. Thomas, Chris Noone, Lauren Bochicchio   +7 more
wiley   +1 more source

Development of Liquid Chromatography on Monolithic Supports-From First Concepts to Real Analytical and Preparative Techniques. [PDF]

Int J Mol Sci
Friganović T, Josić D.
europepmc   +1 more source

The Rice Stripe Virus p2 Interacts With Lsm1 and Disrupts the Lsm1‐Lsm4 Complex to Facilitate the Viral infection

Molecular Plant Pathology, Volume 27, Issue 5, May 2026.
RSV p2 binds Lsm1, disrupting Lsm1‐Lsm4 association and impairing decapping‐dependent mRNA decay in P‐bodies, leading to the accumulation of unstable mRNAs and enhanced RSV infection. ABSTRACT Processing bodies (P‐bodies) play central roles in RNA metabolism and in the regulation of viral infection.
Anqi Hu, Zizhou Zhao, Minjie Shen, Yi Chen, Ying Chen, Miaomiao Li, Lin Lin, Hongying Zheng, Jiejun Peng, Yan Liang, Jianping Chen, Fei Yan, Yuwen Lu   +12 more
wiley   +1 more source