Results 51 to 60 of about 21,642 (287)

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

Advanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn, Wenjing Wang, Yao Qin, Lili Yan, Stephan Scheeff, Xu He, Qiong Wu, Yue Lin, Jinsai Shang, Xin Ye, Jing Liu, Kailei Sun, Chun Wai Yeung, Junzhe Huang, Zhenghui Chen, Xiaodong Liu, Yiqun Geng, Shannon Wing Ngor Au, Bonaventure Y. Ip, Ho Ko, Billy Wai‐Lung Ng   +20 more
wiley   +1 more source

Nano-LC with new neutral monolith for biomolecule separation

Green Analytical Chemistry
A new capillary monolith based on the co-polymerization of 2-napthylmethacrylate (NMM) as the functional monomer and trimethylolpropane trimethacrylate as the crosslinker was introduced for nano-LC.
Cemil Aydoğan, Sinan Bayındır, Halise Avcil, Bayram Yurt   +3 more
doaj   +1 more source

Compressible and Recyclable Monolithic g-C3N4/Melamine Sponge: A Facile Ultrasonic-Coating Approach and Enhanced Visible-Light Photocatalytic Activity

Frontiers in Chemistry, 2018
Powdery photocatalysts seriously restrict their practical application due to the difficult recycle and low photocatalytic activity. In this work, a monolithic g-C3N4/melamine sponge (g-C3N4/MS) was successfully fabricated by a cost-effective ultrasonic ...
Ye Yang, Ye Yang, Qian Zhang, Ruiyang Zhang, Tao Ran, Wenchao Wan, Ying Zhou, Ying Zhou   +7 more
doaj   +1 more source

Tracing lateral subsurface flow in layered soils by undisturbed monolith sampling, targeted laboratory experiments, and model‐based analysis

Vadose Zone Journal, 2022
Lateral subsurface flow (LSF) is a phenomenon frequently occurring in the field induced by local water saturation along horizon boundaries under nonequilibrium conditions.
Annelie Ehrhardt, Kristian Berger, Vilim Filipović, Thomas Wöhling, Hans‐Jörg Vogel, Horst H. Gerke   +5 more
doaj   +1 more source

Cigarette filter butts-derived activated carbon with free binder electrode design for solid-state supercapacitor application

Communications in Science and Technology, 2023
The aim of this research is to formulate activated carbon monolith from hazardous waste of cigarette filter butts (CFB) for electrode material monolith design in solid-state supercapacitor application.
Yanuar Hamzah, Erman Taer, Apriwandi Apriwandi, Faridah Lisa Supian, Niloofar Mozaffari, Nastaran Mozaffari   +5 more
doaj   +1 more source

A Roadmap for Migration System-Architecture Decision by Neutrosophic-ANP and Benchmark for Enterprise Resource Planning Systems

IEEE Access, 2021
The selection of the system-architecture is critical step in software-engineering lifecycle. Unfortunately, the selecting a suitable architecture is a hard mission. The difficulty of the adopting architecture increases in inconsistence case as in SOA and
Amany A. Slamaa, Haitham A. El-Ghareeb, Ahmed Aboelfetouh Saleh   +2 more
doaj   +1 more source

Template-free synthesis of polystyrene monoliths for the removal of oil-in-water emulsion

Scientific Reports, 2017
Oil-in-water emulsions are harmful to both humankind and environment. Frequent oil spill disasters make it urgent to develop low cost and high-efficiency materials for the treatment of oil-in-water emulsions.
Guowei Wang, Bin Yu, Shiguo Chen, Hiroshi Uyama   +3 more
doaj   +1 more source

Understanding the Adsorption Capacity for CO₂ in Reduced Graphene Oxide (rGO) and Modified Ones with Different Heteroatoms in Relation to Surface and Textural Characteristics

Applied Sciences, 2021
Reduced graphene oxide is a material that has a variety of applications, especially in CO2 adsorption. The study of this research is the preparation of reduced graphene oxide with different heteroatoms and how the adsorption capacity is changed.
Nikolaos Politakos, Tomás Cordero-Lanzac, Radmila Tomovska   +2 more
doaj   +1 more source

Dissimilar Materials Bonding Using Epoxy Monolith

, 2018
The epoxy monolith with a highly porous structure is fabricated by the thermal curing of 2,2-bis­(4-glycidyloxyphenyl)­propane and 4,4′-methylenebis­(cyclohexylamine) in the presence of poly­(ethylene glycol) as the porogen via polymerization-induced ...
Yukihiro Nishimura (5491910), Fai Uehara (5491904), Akikazu Matsumoto (1737223), Yuka Sugimoto (5491907)   +3 more
core   +1 more source

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

Advanced Science, EarlyView.
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang, Shihui Lin, Tianyu Wu, Zhixin Zhang, Hong Zhou, Xue Hong, Youhua Liu   +6 more
wiley   +1 more source