Results 91 to 100 of about 365,708 (323)

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

open access: yesExperimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Long‐term impact of stressful life events on breast cancer risk: A 36‐year genetically informed prospective study in the Finnish Twin Cohort

open access: yesInternational Journal of Cancer, Volume 158, Issue 6, Page 1489-1497, 15 March 2026.
What's new? Breast cancer results from a combination of genetic and environmental causes, and the cumulative effect of stressful life events may be a contributing factor. Here, the authors analyzed data from cohort and twin‐pair studies including 36 years of follow‐up to find out how stressful life events affect breast cancer risk. They found that even
Elissar Azzi   +5 more
wiley   +1 more source

Marital Status and Unobserved Heterogeneity - Do twins suggest a genetic inheritance? [PDF]

open access: yes
The purpose of this study is to reveal the importance of unobserved heterogeneity on marital status. The results for monozygotic (identical) and dizygotic twins indicate an important genetic component in marital status.
Nilsson, William
core   +1 more source

Stem-Like Adaptive Aneuploidy and Cancer Quasispecies [PDF]

open access: yes, 2013
We analyze and reinterpret experimental evidence from the literature to argue for an ability of tumor cells to self-regulate their aneuploidy rate. We conjecture that this ability is mediated by a diversification factor that exploits molecular mechanisms
Napoletani, Domenico   +2 more
core   +4 more sources

Discordance in monozygotic Parkinson's disease twins – continuum or dichotomy?

open access: yesAnnals of Clinical and Translational Neurology, 2019
Differences in concordance rates between monozygotic and dizygotic twin pairs with Parkinson's disease (PD) have been used to estimate genetic influences in PD pathogenesis.
Alexander Balck   +6 more
doaj   +1 more source

Monozygotic twins discordant for constitutive BRCA1 promoter methylation, childhood cancer and secondary cancer

open access: yesEpigenetics, 2012
We describe monozygotic twins discordant for childhood leukemia and secondary thyroid carcinoma. We used bisulfite pyrosequencing to compare the constitutive promoter methylation of BRCA1 and several other tumor suppressor genes in primary fibroblasts ...
D. Galetzka   +12 more
semanticscholar   +1 more source

CRISPR‐Cas9‐Generated TXNDC15 c.560delA Homozygous Mouse Model Exhibits Meckel–Gruber Syndrome Phenotype

open access: yesgenesis, Volume 64, Issue 1, February 2026.
ABSTRACT To determine whether TXNDC15 variation causes Meckel–Gruber syndrome (MKS), we assessed the pathogenicity of the frameshift variant c.560delA. A CRISPR–Cas9 generated mouse model carrying the equivalent Txndc15 c.512delA mutation was analyzed at embryonic day 15.5.
Yang Liu   +10 more
wiley   +1 more source

Does Early Life Health Predict Schooling Within Twin Pairs? [PDF]

open access: yes
A large number of studies in labor economics estimate the returns to schooling using data on monozygotic twins, under the assumption that educational attainment is random within twin pairs. This exogeneity assumption has been commonly questioned, however,
Lundborg, Petter   +2 more
core  

Identifying Causal Genotype–Phenotype Relationships for Population‐Sampled Parent–Child Trios

open access: yesGenetic Epidemiology, Volume 50, Issue 1, February 2026.
ABSTRACT The process by which genes are transmitted from parent to child provides a source of randomization preceding all other factors that may causally influence any particular child phenotype. Because of this, it is natural to consider genetic transmission as a source of experimental randomization.
Yushi Tang   +2 more
wiley   +1 more source

Beyond DNA: Epigenetics and Proteomics in Forensic Science [PDF]

open access: yes, 2016
The use of genetic evidence in criminal cases is well established and has improved the public opinion and credibility of forensic science. However, several shortcomings associated with current genetic profiling techniques exist. Scientific research aimed
Eilerts, Diane F
core   +1 more source

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