Results 61 to 70 of about 67,325 (296)

Brain Imaging Phenotypes Associated with Polygenic Risk for Essential Tremor

Movement Disorders, EarlyView.
Abstract Essential tremor (ET) is a common movement disorder with a strong genetic basis. Magnetic resonance imaging (MRI), particularly diffusion‐weighted MRI (dMRI) and T1 MRI, have been used to identify brain abnormalities of ET patients. However, the mechanisms by which genetic risk affects the brain to render individuals vulnerable to ET remain ...
Miranda Medeiros, Alexandre Pastor‐Bernier, Houman Azizi, Zoe Schmilovich, Charles‐Etienne Castonguay, Peter Savadjiev, Jean‐Baptiste Poline, Etienne St‐Onge, Fan Zhang, Lauren J. O'Donnell, Ofer Pasternak, Yashar Zeighami, Patrick A. Dion, Alain Dagher, Guy A. Rouleau   +14 more
wiley   +1 more source

Changes in Gene Sequence that Cause Discordances Involving Disease in Monozygotic Twins [PDF]

, 2021
Identical twins or, monozygotic twins, occur when the egg in a mother is fertilized, but one zygote divides into two separate embryos. Monozygotic twins are considered to be genetically identical, but most twins often display discordances, some involving
Jacques, Kacie
core   +1 more source

Genetics Influences Telomere Length in Parkinson's Disease: A Study in Monozygotic Discordant Twins

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) results from complex interactions among environmental, genetic, and aging factors. Telomeres, which ensure chromosome stability, naturally shorten with cell division, contributing to aging and cellular senescence.
Letizia Straniero, Valeria Rimoldi, Emanuele Cereda, Giulia Soldà, Daniela Calandrella, Stefano Duga, Samanta Mazzetti, Graziella Cappelletti, Ioannis U. Isaias, Gianni Pezzoli, Rosanna Asselta   +10 more
wiley   +1 more source

The (11-22) and (-12-16) twinning modes modelled by obliquity correction of a (58deg, a+2b) prototype stretch twin [PDF]

Acta Crystallographica, 2018, A74, 44-53, 2017
The {11-22} and {11-26} twinning modes were recently put in evidence by Ostapovets et al. (Phil. Mag, 2017)and interpreted as {101-2}-{101-2} double-twins formed by a simultaneous action of two twinning shears. We propose another interpretation in which the twinning modes result from a one-step mechanism based on the same (58deg, a+2b) prototype ...
arxiv   +1 more source

The origin of monozygotic twinning

Reproductive BioMedicine Online, 2002
The incidence of monozygotic twinning appears to be increasing within the field of assisted human reproduction. Many theories have been put forward as to how and when this occurs. Whatever the cause, the normal events of embryo development, which necessarily involve axis formation, patterning and polarization, need to be adhered to in order to obtain a
openaire   +3 more sources

Genetic and environmental contributions to the associations between midlife personality and late‐life metabolic health

Obesity, EarlyView.
Abstract Objective Personality traits such as conscientiousness and emotional stability are consistently linked with better metabolic health, but there is limited evidence on the etiology of these associations and their robustness across the life‐span. Methods Therefore, we estimated phenotypic, genetic, and unique environmental associations of traits ...
Colin D. Freilich, Jacob J. Kunkel, Keely A. Dugan, Elise J. Vomacka, Adolfo G. Cuevas, Kristian Markon, Matt McGue, Glenn I. Roisman, Robert F. Krueger   +8 more
wiley   +1 more source

Comparing Venous vs. Capillary Blood Collection Methods for Proteomic Measurement in Peripheral Blood

PROTEOMICS – Clinical Applications, EarlyView.
ABSTRACT Background Capillary blood collection has a number of advantages over venous collection, especially in the context of increasing decentralized clinical trials and field‐based testing. No studies are available comparing venous versus capillary blood collection for proteomics measurement.
Mary Ni Lochlainn, Nathan J. Cheetham, Mario Falchi, Paolo Piazza, Claire J. Steves   +4 more
wiley   +1 more source

Comparison of Occlusal Indices and Dental Arch Dimensions in Monozygotic Twins

پزشکی بالینی ابن سینا, 2007
Introduction & Objective: The study of monozygotic twins is a valuable method for distinguishing the genetic and environmental etiologic factors. The purpose of this study was comparison between occlusal indices and dental arch dimensions in monozygotic ...
Seyyed Mostafa Abtahi
doaj  

Multi‐Omic Associations of Epigenetic Age Acceleration Are Heterogeneously Shaped by Genetic and Environmental Influences

Aging Cell, EarlyView.
The connections between epigenetic age acceleration (EAA) and the multi‐ome, as well as the extent to which these connections are driven by genetic and environmental factors, remain underexplored. We identified blood proteins, metabolites, and exposures associated with EAA in young adults and, using twin study designs, show that these associations are ...
Gabin Drouard, Sannimari Suhonen, Aino Heikkinen, Zhiyang Wang, Jaakko Kaprio, Miina Ollikainen   +5 more
wiley   +1 more source

Computation of twin-width of graphs [PDF]

arXiv, 2022
Twin-width is a recently introduced graph parameter. In this article, we compute twin-width of various finite graphs. In particular, we prove that the twin-widths of finite graphs with 4 and 5 vertices are less than equal to 1 and 2, respectively. We show that the constructions of dual graph and line graph do not preserve twin-width.
arxiv