Results 141 to 150 of about 419,487 (262)
, 1920 Marketing brochure announcing many activities and destinations on the hotel grounds and around the Peninsula to attract ...
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AI‐Designed Cyclic Peptides Enable Controllable Modulation of the CD28 Immune Checkpoint
Advanced Science, EarlyView.AI‐designed cyclic peptides enable controllable modulation of the CD28 immune checkpoint through reversible disruption of CD28‐CD80/CD86 interactions. The lead peptide, CIP‐3, suppresses T‐cell activation without intrinsic agonist activity, demonstrates dose‐dependent efficacy in a murine colitis model, and attenuates inflammatory cytokine production ...
Katarzyna Kuncewicz +4 more
wiley +1 more source
Advanced Science, EarlyView.This perspective proposes a cohesive machine learning strategy to decode microplastic aging. It advocates for Federated Learning to dismantle global data silos and introduces the TRACE framework (TRansport, Aging, Corona, Ecotoxicity). By integrating physics‐informed modeling with causal discovery, this approach bridges the laboratory‐field gap to ...
Yaping Lyu +6 more
wiley +1 more source
, 1926 The Monterey Peninsula, California at its best; "Where the mountains look on the forest, and the forest looks on the ...
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Advanced Science, EarlyView.Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg +18 more
wiley +1 more source
Anna Pavlova with Pierre Vladimiroff in Invitation to the dance [picture] /
, 1929 Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11557488 ...
Luke, Monte, 1885-1962.
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Lessons From Drug Discovery for Cryoprotective Agent Design: An AI‐Oriented Perspective
Advanced Science, EarlyView.Cryoprotectant design is reframed through the lens of drug discovery as a multiparameter optimization problem. This perspective highlights how AI and systematic design strategies could enable safer, more effective cryoprotectants, while identifying key limitations that currently constrain predictive progress in cryobiology. ABSTRACT Cryopreservation is
Dominika Wilczok +4 more
wiley +1 more source
Advanced Science, EarlyView.Bulk FePd2Te2 contains sparse interlayer Pd–Te covalent bonds, giving it unexpectedly low exfoliation energy and enabling van der Waals‐like exfoliation. Cleaving these bonds during exfoliation makes the monolayer magnetically distinct from the bulk: magnetic anisotropy energy increases, and the strain‐response coefficient of the magnetic moment ...
Huaiyuan Zhao +7 more
wiley +1 more source
AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling
Advanced Science, EarlyView.This review unites experiments, physics‐based simulations, and AI as a synergistic triad for protein dynamics modeling. It highlights integrative strategies, resolves sampling and forcefield bottlenecks, and outlines challenges and future directions for accurate, interpretable conformational ensemble prediction.
Chen Shi +4 more
wiley +1 more source
, 2016 Il volume ricostruisce il discorso pubblico intorno al massacro di Monte Sole (Marzabotto, 1944) nell'Italia repubblicana. Il saggio introduttivo individua le fasi di tale dibattito nel quadro della discussione sulla memoria collettiva della guerra e ...
VENTURA, ANDREA, BALDISSARA, LUCA
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