Results 61 to 70 of about 4,086 (149)

Persistence of quantal synaptic vesicle recycling in virtual absence of dynamins

The Journal of Physiology, Volume 603, Issue 20, Page 6161-6184, October 15, 2025.
Abstract figure legend Figure depicts the key finding from this study. While loss of all dynamins severely debilitates synaptic vesicle retrieval following repetitive activity, retrieval and recycling of individual synaptic vesicles following spontaneous fusion or sparse stimulation are minimally affected.
Olusoji A. T. Afuwape, Natali L. Chanaday, Merve Kasap, Lisa M. Monteggia, Ege T. Kavalali   +4 more
wiley   +1 more source

Age‐Dependent Histone Deacetylase 3 Regulation by βA3/A1‐Crystallin and Inositol Hexaphosphate in Retinal Pigmented Epithelial Cells Reveals a Novel Pathway in Age‐Related Macular Degeneration

Aging Cell, Volume 24, Issue 9, September 2025.
βA3/A1‐crystallin regulates HDAC3 activity and epigenetic processes in the RPE. (A) The illustration demonstrates that βA3/A1‐crystallin plays a crucial role in maintaining IPMK protein expression, which in turn activates HDAC3. (B) When βA3/A1‐crystallin is absent (Cryba1 KO ), IPMK protein expression decreases, resulting in the deactivation of HDAC3.
Sujan Chatterjee, Sayan Ghosh, Zachary Sin, Vishnu Suresh Babu, Loretta Viera Preval, Emily Davis, Nguyen Tran, Sridhar Bammidi, Pooja Gautam, Stacey Hose, Yuri Sergeev, Miguel Flores‐Bellver, Kevin Ritter, Henning J. Jessen, Issam Al Diri, Debasish Sinha, Prasun Guha   +16 more
wiley   +1 more source

Nonunion of ulnar diaphysis after Monteggia fracture of a right forearm in a 55-year-old patient - Are all methods effective? Case report

Journal of Education, Health and Sport, 2019
Fractures of the forearm make up about 10-14% of all fractures. Monteggia lesions account for 1-6% of the forearm fractures. The eponym “Monteggia fracture” is a term used for fracture of ulnar proximal shaft with concomitant dislocation of the radial ...
Marcin Bąk, Bartosz Potoczniak, Artur Dziedzic, Łukasz Kozak, Tomasz Blicharski, Urszula Dziedzic, Teresa Massalska-Małecka, Jaromir Jarecki   +7 more
doaj   +3 more sources

A novel variant of type-II Monteggia equivalent in an adult: A case report with a 6-year follow-up

Trauma Case Reports
Case: An 18-year-old right-handed male student presented after a road-traffic-accident; he had type-II Monteggia fracture dislocation associated with ipsilateral type-I capitellum fracture and comminuted lateral condyle avulsion fracture.
Zackariya Mohamed, Owais Ahmed, Devendra Agraharam, Jafri Sayyadshadab Shahidali, Muthukumar Soundararajan, Dheenadhyalan Jayaramaraju, Shanmuganathan Rajasekaran   +6 more
doaj   +1 more source

Radial head anterior dislocation and ulna bowing in children

PAMJ Clinical Medicine, 2020
A 11 year old boy is examined three days after going to the emergency room, in consultation with orthopaedic surgery for right elbow pain after a fall on the hand.
Mohammed Hajjioui, Najia Hajjioui
doaj   +1 more source

Electrical Stimulation‐Induced Muscle Damage Alters Hippocampal BDNF Signaling

European Journal of Neuroscience, Volume 62, Issue 6, September 2025.
Electrical stimulation (ES) causes muscle damage, local inflammation (↑IL‑1β, CD68), muscular satellite cells (MuSCs) differentiation (↑PAX7, MyoD1), and upregulation of FNDC5/Irisin attributable in part to MuSCs. While FNDC5/Irisin normally mediates beneficial muscle‑to‑brain dialogue, ES‑induced inflammation‐linked signal generates maladaptive cues ...
Julien Wirtz, Rémi Chaney, Marina Cefis, Alexandre Méloux, Yuan Wang, Stéphanie Lemaire, Aurore Quirié, Julien Delezie, Gilles Gouspillou, Anne Prigent‐Tessier, Philippe Garnier   +10 more
wiley   +1 more source

Unraveling Hierarchical Brain Dysfunction in Major Depressive Disorder: A Multimodal Imaging and Transcriptomic Approach

Human Brain Mapping, Volume 46, Issue 10, July 2025.
Dysfunctional hierarchy in major depressive disorder (MDD) features decreased SDI in regions linked to high‐order cognitive functions, like the prefrontal, parietal, and orbitofrontal cortices. Conversely, areas related to low‐level sensory‐motor functions, the somatosensory cortex, showed increased SDI in MDD.
Chen Xiayan, Dai Haowei, Niu Lijing, Chen Zini, Xiaoyue Li, Zeng Yuanyuan, Zhu Qingzi, Lin Kangguang, Zhang Ruibin   +8 more
wiley   +1 more source

Role of Serum Brain‐Derived Neurotrophic Factor as a Biomarker of Chronic Pain in Older Adults

European Journal of Pain, Volume 29, Issue 5, May 2025.
ABSTRACT Background Serum brain‐derived neurotrophic factor (BDNF) has emerged as a promising biomarker for chronic pain (CP) research and treatment. Yet, most human studies have been limited by small sample sizes, inadequate control of confounders and a lack of focus on sex and mental health differences.
R. Ortolá, M. Sotos‐Prieto, A. Carballo‐Casla, S. Cabello‐Plan, Aida Koni, V. Mustieles, L. M. García‐Segura, A. R. Artalejo, F. Rodríguez‐Artalejo, E. García‐Esquinas   +9 more
wiley   +1 more source

The Monteggia fracture : series of 20 cases

The Pan African Medical Journal, 2014
The Monteggia fracture is one of the pitfalls of conventional diagnosis of upper limb trauma. Through a retrospective study of 20 cases diagnosed at the Department of Orthopaedic Surgery and Traumatology, University Hospital Center, Ibn Sina, Mohamed V ...
Aniss Chagou, Abdelkarim Rhanim, Mohammed Saleh Berrada   +2 more
doaj   +1 more source

The Monteggia fracture: series of 20 cases [PDF]

, 2016
The Monteggia fracture is one of the pitfalls of conventional diagnosis of upper limb trauma. Through a  retrospective study of 20 cases diagnosed at the Department of Orthopaedic Surgery and Traumatology,  University Hospital Center, Ibn Sina, Mohamed V
Chagou, Aniss, Rhanim, Abdelkarim, Berrada, Mohammed Saleh   +2 more
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