Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Smoke-free law did affect revenue from gaming in Delaware [PDF]
A paper recently published in the journal Tobacco Control purports to show that the implementation of a smoking prohibition in Delaware had no statistically significant effect on the revenues of three gaming facilities in that state. After correcting for
Michael R. Pakko
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Employment Effects of Early Interventions on Job Search Programs [PDF]
, 2004 We investigate the dependence of the program effect on varying entry times for a low cost job-search assistance program in Austria. The Austrian targeting policy is to admit every unemployed to a job-search program before the fourth month.
Hofer, Helmut, Weber, Andrea Maria
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Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Intertemporal Substitution in Maternal Labor Supply: Evidence using State School Entrance Age Laws [PDF]
In this paper, I propose a new framework to study the intertemporal labor supply hypothesis. I use an exogenous source of variation in maternal net earning opportunities, generated through school entrance age of children, to study intertemporal labor ...
Barua, Rashmi
core +1 more source
An analysis of the price behaviour of selected vegetables at a New Zealand auction : a thesis presented in partial fulfillment of the requirements for the degree of Master of Business Studies at Massey University [PDF]
, 1987 The immediate and short run behaviour of prices and volumes of eighteen vegetables at auction are examined. The objectives were to describe the behaviour of weekly prices and volumes and to investigate various relationships.
Wright, Stephen John
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Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Reflections on the continuing efforts on restructuring of IEJME [PDF]
, 2011 nternational Electronic Journal of Mathematics Education (IEJME) as an international journal has been gaining higher prominence in the international community of mathematics educators since the new structure has been in effect. We will briefly reflect on
Zembat, Ismail O.
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source