Results 261 to 270 of about 52,295 (325)

Exploration of structure–activity relationship of 2,4‐diaminopyrimidine derivatives as hematopoietic progenitor kinase 1 inhibitors

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Targeting HPK1 is a promising strategy to restore T‐cell anti‐tumor immunity. We report the design and synthesis of novel 2,4‐diaminopyrimidine derivatives, focusing on systematic structure–activity relationship (SAR) analysis These findings identify key structural features for potent HPK1 inhibition, facilitating the discovery of next‐generation ...
Heechan Shin   +3 more
wiley   +1 more source

A Dual Luminescent and Chromogenic Pt-NCN Complex for the Detection of GTP and CTP in Aqueous Media. [PDF]

open access: yesInorg Chem
Valdes-García J   +8 more
europepmc   +1 more source

Real‐time biosensing of Parkinson's disease biomarkers via NIR‐activated upconversion nanoparticles

open access: yesBMEMat, EarlyView.
Schematic illustration of the luminescence resonance energy transfer‐driven core‐shell‐shell UCNPs (cssUCNPs@Fluo4) nanoprobe for simultaneous monitoring of Ca²⁺‐temperature dynamics in Parkinson's disease models. Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with incompletely understood pathophysiology, necessitating ...
Jialin Liu   +9 more
wiley   +1 more source

Effect of the BD132 Dendron Against <i>Candida tropicalis</i>: Inhibition of Biofilm Formation and Enzymatic and Structural Alterations. [PDF]

open access: yesPharmaceutics
García-Porcel E   +4 more
europepmc   +1 more source

New parajeilongviruses detected in bats but not in humans: assays for screening and diagnostic purposes. [PDF]

open access: yesArch Virol
Pulkkinen E   +13 more
europepmc   +1 more source

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