Results 131 to 140 of about 123,303 (312)

Psychological mechanisms underlying morality in sport [PDF]

open access: yes, 2019
Sport is believed to promote prosocial values, such as fair play and sportsmanship (Shields & Bredemeier 1995). However, sport can also promote anti-social behaviors, such as cheating and gamesmanship (Kavussanu 2019). Experiences of antisocial behaviors
Hurst, P.
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Happiness, Morality, and Game Theory [PDF]

open access: yes
Non-cooperative Games, Happiness, Morality.
Luca Zarri
core  

Avoiding Reproduction: Law, Rights and Morality [PDF]

open access: yes, 2016
As medical technology has advanced, so too have our attitudes towards the level of control we can or should expect to have over our procreative capacities.
Clayton Thompson, J.
core  

Moral Praise and Moral Performance

open access: yesEuropean Journal of Philosophy
AbstractAccording to some, luck forms an inevitable part of admirable moral agency. According to others, it is incompatible with a basic principle of moral worth. What's the issue? Is there a ‘problem’ of moral luck; or are there many, or none? With reference to the practice of moral praise, I suggest that there is no single problem of moral luck as ...
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

The law-morality relation revisited: A challenge to established traditions by the Australian sceptical approach

open access: yes, 2006
Three long-established, competing frameworks for understanding the law-morality relation - the individual reason-based tradition (represented here by Rawls), the communitarian tradition (MacIntyre and Cotterrell) and the utilitarian or positivist ...
Wickham, G.
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Morality-driven data forwarding with privacy preservation in mobile social networks

open access: yes, 2012
Morality-driven data forwarding with privacy preservation in mobile social ...
R Lu (13669768)   +5 more
core  

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