NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
Inspecting the factors of individualizing and binding moral value orientation in the Moral Foundations Questionnaire-2 for validation-a re-analysis of data from pre-service teachers in Ghana. [PDF]
Wild S, Fobi D, Möhring M.
europepmc +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Navigating the complexities of morality and culture: a critical commentary on the special topics issue "culture and morality: the things we value". [PDF]
Xie T, Wu MS.
europepmc +1 more source
Morality-related and revolution-related arguments in Facebook discussions concerning veganism
Giuditta Spassini
openalex +2 more sources
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini +7 more
wiley +1 more source
Polarization in the COVID-19 pandemic: The impact of vaccination status and conspiracy theories. [PDF]
Willemsen L +4 more
europepmc +1 more source
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen +6 more
wiley +1 more source
Correction: A shifting baseline theory of debates over potential lynx and wolf reintroductions to Scotland. [PDF]
Whitehead T, Hare D.
europepmc +1 more source

