Results 41 to 50 of about 695,624 (295)
Giner on the Socio-genesis of Morality [PDF]
, 2013 I discuss the main claims in a new book on the origins of morality . These are: i) our time, far from being the twilight of morality, is the first time in human history when a universalistic and autonomous morality has emerges as a social phenomenon, not
Cremaschi, Sergio
core +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Moraliteit, die opdringerige en die voorwaardelike
Koers : Bulletin for Christian Scholarship, 2010 Morality, the obtrusive and the conditional The secularist (immanentist), historicist and pluralistic nature of current thinking disables the articulation of transcendental conditions for morality.
M.F. Heyns
doaj +1 more source
Проблема дослідження моральності в когнітивній парадигмі. (The problem of research morality in cognitive paradigm.) [PDF]
, 2010 У статті піднімається проблема дослідження моральності в сучасній когнітивній психології. Описуються три шляхи формування моральності – через страх покарання, емпатійний та рефлексивний.
Матласевич , О. В. (О. Matlasevych)
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Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
The Function of Normative Process‐Requirements [PDF]
, 2012 This paper discusses whether rationality, morality or prudence impose process‐requirements upon us. It has been argued that process‐requirements fulfil two essential functions within a system of rational, moral or prudential requirements. These functions
Fink, Julian
core +1 more source
Theorizing Moral Cognition: Culture in Action, Situations, and Relationships [PDF]
, 2020 Dual-process theories of morality are approaches to moral cognition that stress the varying significance of emotion and deliberation in shaping judgments of action.
Luft, Aliza
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Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source