Results 81 to 90 of about 785,945 (409)

Contractualism and the Second-Person Moral Standpoint [PDF]

open access: yes, 2014
This article explores Darwall’s second-­‐personal account of morality, which draws on Fichte’s practical philosophy, particularly Fichte’s notions of a summons and principle of right. Darwall maintains that Fichte offers a
Pauer-Studer, Herlinde
core  

Delegating and Distributing Morality: Can We Inscribe Privacy Protection in a Machine? [PDF]

open access: yes, 2006
This paper addresses the question of delegation of morality to a machine, through a consideration of whether or not non-humans can be considered to be moral. The aspect of morality under consideration here is protection of privacy.
Adam, AE
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

The Roman Catholic conceptualisation of morality: Its essence and distinctive character

open access: yesVerbum et Ecclesia
Over the course of its history Catholicism has generated several different conceptions of morality. The early medieval church conceived morality primarily in terms of caritas and other virtues, the modern church generated a legalistic conception of ...
Stephen J. Pope
doaj   +1 more source

Understanding Catholic morality [PDF]

open access: yes, 1999
Willems, Elizabeth. Understanding Catholic morality.
O\u27Connor, Thomas St. James
core   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

The Roots of Right and Wrong: Do Concepts of Innate Morality Reduce Intuitive Associations of Immorality With Atheism?

open access: yesSecularism and Nonreligion, 2015
Atheists are frequent targets of prejudice and discrimination. Previous research suggests that anti-atheist prejudice may stem in part from perceptions of religion as an ultimate basis for morality: without God, why do good (or not do bad)?
Tommy L Mudd   +3 more
doaj   +1 more source

The Community of Nursing: Moral Friends, Moral Strangers, Moral Family [PDF]

open access: yes, 2008
Unlike bioethicists who contend that there is a morality common to all, H. Tristan Engelhardt (1996) argues that, in a pluralistic secular society, any morality that does exist is loosely connected, lacks substantive moral content, is based on the ...
Laabs, Carolyn A.
core   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Aspects of folk morality: Objectivism and relativism [PDF]

open access: yes, 2016
Most moral philosophers work under the assumption that ordinary folk morality is committed to objectivism—that ordinary folk view morality in absolute terms.
Sarkissian, Hagop
core  

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