Results 81 to 90 of about 174,525 (297)

Mastering moral misery: Emotional and coping responses to intragroup morality (vs. competence) evaluations [PDF]

open access: yes, 2016
In social groups, individuals are often confronted with evaluations of their behaviour by other group members and are motivated to adapt their own behaviour accordingly.
Ellemers, N.   +8 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

In or Out? How the perceived morality (vs. competence) of prospective group members affects acceptance and rejection [PDF]

open access: yes, 2017
When is an individual likely to be accepted or rejected by a group? This research investigates responses towards prospective group members depending on how they compare to the group in terms of their perceived morality or competence.
Rutjens, Bastiaan T   +17 more
core   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

A Dual Mechanism of Cognition and Emotion in Processing Moral-Vertical Metaphors

open access: yesFrontiers in Psychology, 2018
A moral concept involves two main factors: moral cognition (indicated by morality) and emotion (indicated by emotionality). The cognitive mechanism underlying moral metaphors on the vertical dimension (e.g., moral-up, immoral-down) was investigated in ...
Dongxue Zhai   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Determinism and the possibility of morality

open access: yesJournal of Islamic Thought and Civilization, 2012
The possibility of morality in a causally determined physical world engages philosophers in a serious debate. Many philosophers think that morality is not possible in a world where everything, including human actions, is determined by antecedent causal ...
Dr. Zahoor H. Baber
doaj  

A Developmental Perspective on the Origins of Morality in Infancy and Early Childhood

open access: yesFrontiers in Psychology, 2018
Key constituents of morality emerge during the first 4 years of life. Recent research with infants and toddlers holds a promise to explain the origins of human morality.
Audun Dahl, Melanie Killen
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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