KRAS mutation analysis by PCR : a comparison of two methods [PDF]
Background: KRAS mutation assays are important companion diagnostic tests to guide anti-EGFR antibody treatment of metastatic colorectal cancer. Direct comparison of newer diagnostic methods with existing methods is an important part of validation of ...
Lucas, Katie +9 more
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Impact of the Specific Mutation in KRAS Codon 12 Mutated Tumors on Treatment Efficacy in Patients with Metastatic Colorectal Cancer Receiving Cetuximab-Based First-Line Therapy: A Pooled Analysis of Three Trials [PDF]
Purpose: This study investigated the impact of specific mutations in codon 12 of the Kirsten-ras (KRAS) gene on treatment efficacy in patients with metastatic colorectal cancer (mCRC).
Zielinski, Christoph C. +12 more
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Deep sequence analysis of non-small cell lung cancer: Integrated analysis of gene expression, alternative splicing, and single nucleotide variations in lung adenocarcinomas with and without oncogenic KRAS mutations [PDF]
KRAS mutations are highly prevalent in non-small cell lung cancer (NSCLC), and tumors harboring these mutations tend to be aggressive and resistant to chemotherapy.
David Rossell +65 more
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Collecting of Carabidae was conducted using pitfall traps at four sites. The first two sites (T1 + T2) were at the slope of Macošská stráň and the other two sites (T3 + T4) at the slope of Vilémovická stráň. The study was done in 2008 and 2009.
Jana Niedobová +2 more
doaj +1 more source
Microsatellite instability, KRAS mutations and cellular distribution of TRAIL-receptors in early stage colorectal cancer. [PDF]
Thus, we evaluated the immunofluorescence pattern of TRAIL-receptors and E-cadherin to assess the fraction of membrane-bound TRAIL-receptors in 231 selected patients with early-stage CRC undergoing surgical treatment only.
Göke, Burkhard +32 more
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Radiokarbonové datování strusky z lokality Habrůvecká bučina [PDF]
Příspěvek je věnován prezentaci výsledků radiokarbonového datování vybraných exemplářů strusky z lokality Habrůvecká bučina v Moravském krasu. Hlavním účelem analýzy bylo upřesnění datace a poskytnutí nového úhlu pohledu na poznatky získané na základě ...
Roman Mikulec +2 more
doaj +1 more source
Habrůvecká bučina – vyhodnocení materiálového souboru [PDF]
Příspěvek se zabývá archeologickým výzkumem provedeným v letech 1995 až 1997 na lokalitě Habrůvecká bučina v Moravském krasu. Hlavním cílem je soupis a analýza současně dostupného nálezového souboru z této lokality.
Roman Mikulec
doaj +1 more source
The number of remarkable species on a locality is an important indicator of locality value. The ecological requirements of the rare species may help to target correct landscape management activities.
Jana Niedobová, Zdeněk Faltýnek Fric
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Recreational mountain biking - a new tool in rural development
Central Europe landscape has been used by humans for many centuries. Balanced cultural landscape provides numerous services from which recreation becomes more and more important.
Alice Kozumplikova +3 more
doaj +1 more source
Flywheel proof mass actuator for active vibration control [PDF]
This paper presents the experimental results of a new proof mass actuator for the implementation of velocity feedback control loops to reduce the flexural vibration of a thin plate structure.
Kras A., Gardonio P.
core +1 more source

