Results 11 to 20 of about 30,968 (78)

KRAS mutation analysis by PCR : a comparison of two methods [PDF]

open access: yes, 2015
Background: KRAS mutation assays are important companion diagnostic tests to guide anti-EGFR antibody treatment of metastatic colorectal cancer. Direct comparison of newer diagnostic methods with existing methods is an important part of validation of ...
Lucas, Katie   +9 more
core   +2 more sources

Impact of the Specific Mutation in KRAS Codon 12 Mutated Tumors on Treatment Efficacy in Patients with Metastatic Colorectal Cancer Receiving Cetuximab-Based First-Line Therapy: A Pooled Analysis of Three Trials [PDF]

open access: yes, 2012
Purpose: This study investigated the impact of specific mutations in codon 12 of the Kirsten-ras (KRAS) gene on treatment efficacy in patients with metastatic colorectal cancer (mCRC).
Zielinski, Christoph C.   +12 more
core   +1 more source

Deep sequence analysis of non-small cell lung cancer: Integrated analysis of gene expression, alternative splicing, and single nucleotide variations in lung adenocarcinomas with and without oncogenic KRAS mutations [PDF]

open access: yes, 2012
KRAS mutations are highly prevalent in non-small cell lung cancer (NSCLC), and tumors harboring these mutations tend to be aggressive and resistant to chemotherapy.
David Rossell   +65 more
core   +1 more source

Ground beetles (Carabidae) from slopes of Macošská stráň and Vilémovická stráň (Protected landscape area of Moravský kras, Czech Republic)

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2011
Collecting of Carabidae was conducted using pitfall traps at four sites. The first two sites (T1 + T2) were at the slope of Macošská stráň and the other two sites (T3 + T4) at the slope of Vilémovická stráň. The study was done in 2008 and 2009.
Jana Niedobová   +2 more
doaj   +1 more source

Microsatellite instability, KRAS mutations and cellular distribution of TRAIL-receptors in early stage colorectal cancer. [PDF]

open access: yes, 2012
Thus, we evaluated the immunofluorescence pattern of TRAIL-receptors and E-cadherin to assess the fraction of membrane-bound TRAIL-receptors in 231 selected patients with early-stage CRC undergoing surgical treatment only.
Göke, Burkhard   +32 more
core   +2 more sources

Radiokarbonové datování strusky z lokality Habrůvecká bučina [PDF]

open access: yesArcheologia Technica
Příspěvek je věnován prezentaci výsledků radiokarbonového datování vybraných exemplářů strusky z lokality Habrůvecká bučina v Moravském krasu. Hlavním účelem analýzy bylo upřesnění datace a poskytnutí nového úhlu pohledu na poznatky získané na základě ...
Roman Mikulec   +2 more
doaj   +1 more source

Habrůvecká bučina – vyhodnocení materiálového souboru [PDF]

open access: yesArcheologia Technica
Příspěvek se zabývá archeologickým výzkumem provedeným v letech 1995 až 1997 na lokalitě Habrůvecká bučina v Moravském krasu. Hlavním cílem je soupis a analýza současně dostupného nálezového souboru z této lokality.
Roman Mikulec
doaj   +1 more source

The Adequacy of Some Collecting Techniques for Obtaining Representative Arthropod Sample in Dry Grasslands

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2014
The number of remarkable species on a locality is an important indicator of locality value. The ecological requirements of the rare species may help to target correct landscape management activities.
Jana Niedobová, Zdeněk Faltýnek Fric
doaj   +1 more source

Recreational mountain biking - a new tool in rural development

open access: yesEcocycles, 2018
Central Europe landscape has been used by humans for many centuries. Balanced cultural landscape provides numerous services from which recreation becomes more and more important.
Alice Kozumplikova   +3 more
doaj   +1 more source

Flywheel proof mass actuator for active vibration control [PDF]

open access: yes, 2023
This paper presents the experimental results of a new proof mass actuator for the implementation of velocity feedback control loops to reduce the flexural vibration of a thin plate structure.
Kras A., Gardonio P.
core   +1 more source

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