Results 91 to 100 of about 931,716 (345)
Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis
Arthritis &Rheumatology, EarlyView.Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm +2 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Evaluate performance of the Predicting Risk of Cardiovascular Disease Events (PREVENT) calculator in rheumatoid arthritis (RA). Methods Patients with RA were matched up to 10 controls on age, sex, and enrollment year using National Veterans Health Administration, Medicare, and National Death Index data (2006–2020).
Tate M. Johnson +13 more
wiley +1 more source
Morbid Obesity Rates Continue to Rise Rapidly in the US
International Journal of Obesity, 2013 Clinically severe or morbid obesity (body mass index (BMI) >40 or 50 kg m−2) entails far more serious health consequences than moderate obesity for patients, and creates additional challenges for providers.
R. Sturm, Aiko Hattori
semanticscholar +1 more source
Impaired Abdominal Skin Sensory Function in Morbid Obesity and After Bariatric Surgery
, 2012 Bariatric surgery reduces body weight, but creates the need for surgical correction of the patient's body shape, especially of the abdomen. the abdominal skin of the ex-obese has a lower quantity of fibrous and non-fibrous components; however, its ...
Garcia, Elvio Bueno [UNIFESP] +3 more
core +1 more source
Morbid Obesity with Severe Hypertension: A Clinical Challenge
, 2022 Background: Morbid obesity is a growing concern among children and adolescents, and is complicated by multitude of morbidities such as diabetes, hypertension, metabolic syndrome, and sleep disturbances.
Sriram Krishnamurthy +3 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó +84 more
wiley +1 more source
Health-related Quality of Life in Adult Patients with Morbid Obesity Coming for Bariatric Surgery
, 2009 Background Obesity has become a major health issue not only in the West but also in Asia. Morbid obesity can lead to much comorbidity and can markedly interfere with quality of life.
張吉仰;黃致錕;張郁瑩;戴啟明;林肇堂;王榮德 +1 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola +14 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić +4 more
wiley +1 more source
Hepatology, EarlyView., 2022 Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan +22 more
wiley +1 more source