Results 151 to 160 of about 1,348,340 (308)

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.
Na Young Lee, Myeung Gi Choi, Ho Jae Ryu, Young Jin Min, Seon Min Kim, Yeonseok Chung, Bo Kyung Koo, Yun Pyo Kang, Won Kim, Ja Hyun Koo   +9 more
wiley   +1 more source

Post-TB care in the UK: a national survey of existing practice. [PDF]

BMJ Open Respir Res
O'Reilly A, Martin CA, Cox SE, Haldar P, Zenner D, Pareek M, Meghji J.   +6 more
europepmc   +1 more source

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

Advanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang, Xu Chen, Haowei Xu, Zhiqi Zeng, Keyu Lu, Yu Mao, Qianru Lv, Hui Shi, Song Liu, Xian Shen, Chunyu Yin, Yang Yang, Yan Guo, Xingyun Wang, Rui Cheng   +14 more
wiley   +1 more source

Effectiveness of Couple-Based Optimal Breastfeeding Promotion and Support Interventions on Child Morbidity in Central Ethiopia: A Cluster-Randomized Controlled Trial. [PDF]

Health Sci Rep
Abageda M, Jena BH, Agde ZD, Anamo WA, Belachew T.   +4 more
europepmc   +1 more source

Comparison of Systemic Inflammation Indices With Post- Cardiac Surgery Mortality and Morbidity [PDF]

Ahmet Ozan Koyuncu, Mehmet Ali Yeşiltaş, Sadiye Deniz Özsoy, Murat Mert   +3 more
openalex   +1 more source

DRD2 Deficiency Underlies Pituitary Adenoma Dependent on Escherichia coli Translocation from the Gut

Advanced Science, EarlyView.
Dopamine receptor D2 (DRD2) deficiency disrupts epithelial barrier integrity in both the gut and pituitary gland, facilitating translocation of gut‐derived Escherichia coli into pituitary tissue. Intratumoral E. coli are phagocytosed by microglia, triggering GSDMD‐dependent pyroptosis and HMGB1 release, which subsequently activates MAPK signaling to ...
Xian‐jun Su, Li Ma, Xi Xiong, Jun‐hua Meng, Qi Wu, Yu Zhang, Shu‐guang Dong, Yue‐fei Wang, Jin‐hu Wu, Qing‐yuan Zeng, Hong‐feng Zhang, Li‐li Li, Liang Meng, Min Peng, Xiao‐dong Huang, Li‐quan Wu, Xiong Wang   +16 more
wiley   +1 more source

Morbidity amongst anaesthetists [PDF]

Anaesthesia, 1982
R J, Keen, C J, Whitaker
openaire   +2 more sources

Smoking-Attributable Mortality, Morbidity, and Economic Costs (SAMMEC) - Smoking-Attributable Mortality (SAM)

United States Department of Health and Human Services. Centers for Disease Control and Prevention, Health Consequences and Costs   +1 more
openalex   +1 more source

The morbidity, viability and growth performance of water buffalo (Bubalus bubalis) calves during the growth phase can be affected by colostrum nutritional components as well as colostrum and calf’s serum non-nutritional components [PDF]

İbrahim Cihangir Okuyucu, Hüseyin Erdem   +1 more
openalex   +1 more source

Vaginal progesterone decreases preterm birth and neonatal morbidity and mortality in women with a twin gestation and a short cervix: an updated meta‐analysis of individual patient data [PDF]

, 2017
Roberto Romero, A. Conde‐Agudelo, Waleed Elrefaie, Line Rode, Maria de Lourdes Brizot, Elçin Çetingöz, Vicente Serra, Eduardo Da Fonseca, Mohamed Sayed Abdelhafez, Ann Tabor, Alfredo Perales, Sonia S. Hassan, K. H. Nicolaides   +12 more
openalex   +1 more source