Results 51 to 60 of about 1,289,189 (314)

Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster, Jae Woo Chung, Maria E. Linn‐Evans, Matthew N. Petrucci, Chiahao Lu, Destiny J. Weaver, Joshua De Kam, Scott E. Cooper, Paul J. Tuite, Aleksandar Videnovic, Michael J. Howell, Colum D. MacKinnon   +11 more
wiley   +1 more source

An investigation performed in a Bangladeshi general hospital on the use of proton pump inhibitors drugs by patients [PDF]

Hospital Pharmacology
Introduction: Proton pump inhibitors (PPIs) are anti-ulcer drugs that have reportedly been used inappropriately in therapeutic settings, raising the risk of adverse effects, drug interactions , and costs.
Sony Tahmina Akter, Alam Md Nur, Hoque Majedul M.   +2 more
doaj   +1 more source

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu, Oliver Robinson, Christina M. Lill, Anna Matton, Raquel Puerta, Pilar Sanz, Merce Boada, Agustín Ruiz, Lefkos Middleton, for the Alzheimer's Disease Neuroimaging Initiative   +9 more
wiley   +1 more source

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou, Carl D. Langefeld, Padmini Sekar, Mary Comeau, Timothy Howard, Tamara N. Kimball, Chen Bowang, Hyacinth I. Hyacinth, Jonathan Rosand, Christopher D. Anderson, Caspar Grond‐Ginsbach, Daniel Woo, Stacie L. Demel   +12 more
wiley   +1 more source

Is ambulance conveyance associated with distance to hospital and patient outcomes? A register-based cohort study in Region Zealand, Denmark, 2017–2022

BMJ Open
Background Non-conveyance, the decision not to transport a patient to a healthcare facility, can result from patient refusal or the ambulance professional’s decision.
Stig Nikolaj Fasmer Blomberg, Signe Amalie Wolthers, Annette Ersbøll, Helle Collatz Christensen, Josefine Tangen Jensen, Thea Palsgaard Møller   +5 more
doaj   +1 more source

Psoriasis and Co-morbidity

Acta Dermato Venereologica, 2020
Psoriasis is associated with multiple co-morbid medical conditions. The purpose of this study is to evaluate the relationships between psoriasis and cardiovascular disease, psoriatic arthritis, mental health conditions, and immune-mediated diseases, respectively.
Erica B Lee, Tsen-Fang Tsai, Mina Amin, Jashin J. Wu   +3 more
openaire   +4 more sources

Smoking and the compression of morbidity [PDF]

Journal of Epidemiology & Community Health, 2000
To examine whether eliminating smoking will lead to a reduction in the number of years lived with disability (that is, absolute compression of morbidity).Multistate life table calculations based on the longitudinal GLOBE study (the Netherlands) combined with the Longitudinal Study of Aging (LSOA, United States of America).the Netherlands.Dutch ...
Caspar W. N. Looman, P.J. Marang-van de Mheen, Johan P. Mackenbach, Wilma J. Nusselder, Dike van de Mheen   +4 more
openaire   +4 more sources

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen, Ali Behram Salar, Abdulkadir Ermis, Erkingul Birday, Lutfu Hanoglu, Bayram Ufuk Sakul   +5 more
wiley   +1 more source

Appendicitis and its associated mortality and morbidity in infants up to 3 months of age: A systematic review

Health Science Reports, 2023
Background and Aims Although appendicitis is rare in young infants, the reported mortality is high. Primary aim of this systematic review was to provide updated insights in the mortality and morbidity (postoperative complications, Clavien‐Dindo grades I ...
Sarah‐May M. L. The, Anne‐Fleur M. H. The, Joep P. M. Derikx, Roel Bakx, Douwe H. Visser, Tim G. J. deMeij, Johannes C. F. Ket, Ernest L. W. vanHeurn, Ramon R. Gorter   +8 more
doaj   +1 more source

Cancer Risk in Patients With Systemic Sclerosis: A Nationwide Cohort Study in South Korea 2004 to 2021

Arthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) is a rare autoimmune disease characterized by tissue fibrosis, vasculopathy, and immune dysregulation. Our objectives were to quantify the overall and site‐specific cancer risks in patients with SSc compared to the general population, examine temporal trends in cancer incidence following SSc diagnosis, and explore ...
Jihyun Na, Su Jin Choi, Sojeong Park, Minae Park, Doo‐Ho Lim   +4 more
wiley   +1 more source