Results 231 to 240 of about 1,251,897 (287)

The womb as the cradle of longevity: Perinatal origins of biological aging

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract The perinatal period is increasingly recognized as an important determinant of biological aging trajectories and disease susceptibility across the lifespan. This narrative review synthesizes current evidence linking intrauterine exposures to adult health outcomes across three biological dimensions: fetal programming, maternal influences, and ...
Sevim Ozge Ozdemir, Ebru Davutoglu
wiley   +1 more source

Deep learning–based automated cervical length measurement improves spontaneous preterm birth risk stratification in women with a borderline short cervix (20–25 mm) at mid‐trimester: A retrospective cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study evaluates whether deep learning (DL)‐based automated cervical length (CL) measurement provides improved risk stratification for spontaneous preterm birth (PTB), compared with conventional CL measurement methods, in women with a borderline short cervix by conventional methods (CL 20–25 mm) on mid‐trimester ultrasound ...
Ju‐Hee Yoon   +6 more
wiley   +1 more source

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Multi‐omics–driven precision medicine

open access: yesiMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li   +20 more
wiley   +1 more source

Hematological and Genotoxic Effects of Subchronic Oral Exposure to a Mancozeb‐Based Fungicide in Female Mice

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The extensive use of pesticides in modern agriculture has raised increasing concerns regarding the potential biological effects of repeated exposure to pesticide residues and commercial formulations. Mancozeb is a widely used ethylene‐bis‐dithiocarbamate fungicide; however, information on its hematological and genotoxic effects following ...
Matheus Henrique Barcelos Figueiredo   +10 more
wiley   +1 more source

Cytotoxic and Genotoxic Effects in Buccal Cells of Sandstone Quarry Workers

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Mineral extraction poses significant occupational health risks, particularly from respirable crystalline silica exposure. Sandstone quarrying generates substantial dust, yet evidence of its genotoxic effects remains limited. This study investigated cytogenotoxic damage in sandstone quarry workers from southern Brazil using the buccal ...
Ana Carolina de Quadros Duarte   +6 more
wiley   +1 more source

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