Results 241 to 250 of about 5,152,307 (277)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

More Than Human:

The Black Scholar, 2016
This chapter suggests that the relation of sociology to materiality is by and large characterized in terms of a forgetting of materiality. Sociological accounts have tended to privilege language, discourse, and culture and assign primary dynamism to the human realm.
openaire   +2 more sources

More Than Humans

2016
This chapter focuses on the ways in which non-human entities can be included in the Relational Ecosystem of the city, such as plants, trees, infrastructures, organizations, sensors, and devices. The methodologies, approaches, technologies, and modalities according to which these scenarios can take form are examined using a variety of approaches and ...
Salvatore Iaconesi, Oriana Persico
openaire   +1 more source

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