Results 211 to 220 of about 6,612,409 (279)

Depth-Wise Changes in Tibial and Femoral Human Knee Joint Cartilage at Different Severities of Osteoarthritis. [PDF]

J Orthop Res
Honkapää K, Eskelinen ASA, Mikkonen S, Ebrahimi M, Finnilä MAJ, Saarakkala S, Korhonen RK, Englund M, Tanska P.   +8 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Transceiver 16-Channel Coaxial-End Dipole Array for Combined Head and C-Spine MRI at 9.4 T. [PDF]

NMR Biomed
Solomakha GA, Glang F, May MW, Mueller S, Walzog J, Aghaeifar A, Bosch D, Bause J, Kraff O, Scheffler K, Quick HH, Avdievich NI.   +11 more
europepmc   +1 more source

Urban Repair, Designing With/For More-Than-Human Life.

Graphical and critical memory of the Summer School held in Malaga in the framework of the Erasmus+ KA2 program Socially Situated Architecture Pedagogies (SArPe). Working in the Bosque Urbano Malaga (BUM), not only as a site of design intervention but also as a space of diverse urban narratives that shape, and are shaped by, those who inhabit it ...
openaire   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

The Sense of Security and Associated Factors Among Older Home Care Clients: A Register Study. [PDF]

Scand J Caring Sci
Mira P, Turja T, Mari A, Johanna E, Marja K.   +4 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Deepening ideas vs. exploring new ones: AI strategy effects in human-AI creative collaboration. [PDF]

PLoS One
Komura K, Yamada S.
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Development and Evaluation of an AI Avatar Educational Tool for Depression and Anxiety: A Qualitative Pilot Study. [PDF]

J Prim Care Community Health
Bleik A, Marr P, Li SA, Kwan D, Ji C, Leblanc K, Meng Y, Papoushek C.   +7 more
europepmc   +1 more source