Results 71 to 80 of about 6,612,409 (279)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Nanoethics for the Plastocene: the value sensitive design of nanofiber materials

Journal of Responsible Innovation
This paper focuses on how to respond appropriately to the problem of the (non-)biodegradability of nanofibers and how the integration of ethics could help.
Michal Trčka, Tereza Stöckelová, David Lukáš, David Svoboda   +3 more
doaj   +1 more source

Advantages and Limitations of Commercially Available Electrocuting Grids for Studying Mosquito Behaviour. [PDF]

, 2013
Mosquito feeding behaviour plays a major role in determining malaria transmission intensity and the impact of specific prevention measures. Human Landing Catch (HLC) is currently the only method that can directly and consistently measure the biting rates
A Seyoum, BG Knols, CN Mbogo, D Collett, Dennis J Massue, EJ Kweka, EM Mathenge, EM Mathenge, EM Mathenge, FO Okumu, FO Okumu, GA Vale, GA Vale, GA Vale, Gerry F Killeen, GF Killeen, H Pates, HD Trung, HJ Overgaard, HM Ferguson, I Tiradoros, JA Scott, JD Lines, JE Urban, JT Griffin, LE Mboera, LW Cohnstaedt, M Odiere, M Sikulu, ML Quiñones, MT Gillies, MT Gillies, MT Gillies, MW Service, N Braimah, Nicodem J Govella, NJ Govella, NJ Govella, NJ Govella, PA Eckhoff, R Laganier, Silas Majambere, SJ Torr, SJ Torr, Steven M Magesa, TB Frick, WHO, WL Kilama, Y Geissbühler, Yeromin Mlacha   +49 more
core   +4 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

When we talk about time, we mean many different things: employing visual mapping to think through more-than-human temporalities in participatory design

Frontiers in Communication
In recent years, the scope of participatory design has broadened to encompass perspectives and approaches beyond the human realm. This expansion requires considering multiple aspects to fully capture ‘more-than-humans’ diversity and concerns.
Hadas Zohar, Luca Simeone, Amalia de Götzen, Nicola Morelli   +3 more
doaj   +1 more source

Generosity in More-than-human Design

Proceedings of DRS
Generosity for more-than-human design suggests an openness to change in grappling with human exceptionalism and nonhuman entanglements. Yet the risks of generosity in design practice are largely unarticulated, and it is unclear how designers might practically encounter and navigate them.
openaire   +3 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Crazy ideas or creative probes?: presenting critical artefacts to stakeholders to develop innovative product ideas [PDF]

, 2007
A number of design practices derive from and develop the notion of critical theory. Notable developers of such “critical design practices” are Dunne & Raby with “critical design”, Sengers and colleagues at Cornell University's Culturally Embedded ...
Bowen, S. J.
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source