Results 1 to 10 of about 3,209 (153)
Upcoming treatments for morphea
Immunity, Inflammation and Disease, 2021 Morphea (localized scleroderma) is a rare autoimmune connective tissue disease with variable clinical presentations, with an annual incidence of 0.4–2.7 cases per 100,000.
Ahmad Reza Dehpour +2 more
exaly +2 more sources
Is adiponectin involved in morphea pathogenesis? – first observational study [PDF]
Frontiers in ImmunologyBackgroundMorphea is a chronic inflammatory condition characterized by fibrosis of the skin and/or subcutaneous tissues. Adiponectin is an adipokine known for its anti-inflammatory and antifibrotic properties.
Adriana Polańska +5 more
doaj +2 more sources
Remote Skin and Blood Sampling for Translational Connective Tissue Disorder Research: A Proof-of-Concept Pilot Study [PDF]
JID InnovationsRemote, noninvasive biospecimen collection methods can address geographic and mobility-related barriers to participation in translational research for connective tissue disorders.
Dany Alkurdi +7 more
doaj +2 more sources
Association of Bullous Lichen Sclerosus and Morphea [PDF]
Clinical Case ReportsLichen sclerosus (LSc) is an inflammatory skin disease of unknown etiology. The coexistence of LSc and morphea in the same lesion is uncommon but exists. Also, there exist a few rare cases of bullous LSc–generalized morphea overlap syndrome.
Seyyede Zeinab Azimi +3 more
doaj +2 more sources
Muscle weakness in a 4-year-old girl: A rare presentation of deep morphea
Indian Journal of Paediatric Dermatology, 2021 Introduction: Morphea is a rare fibrosing disorder of the skin and underlying tissues. Deep morphea involves the deep dermis, subcutis, fascia, muscle, and bone. The above structures may be involved independently or in combination.
Mary Augustine, Sumedha Ballal
doaj +1 more source
Autoantigen microarrays reveal myelin basic protein autoantibodies in morphea
Journal of Translational Medicine, 2022 Background Morphea is an autoimmune, sclerosing skin disorder. Despite the recent emphasis on immune dysregulation in morphea, the role of autoantibodies in morphea pathogenesis or utility as biomarkers are poorly defined.
Jane L. Zhu +12 more
doaj +1 more source
The role of infection in morphea disease [PDF]
Reviews in Clinical Medicine, 2015 Morphea is a skin disorder that leads to the sclerosis of the dermis and subcutaneous tissue. In epidemiologic studies, the incidence rate of approximately 0.4 to 2.7 per 100,000 people has been reported that is equal in adults and children.
Fatemeh Farhangdoost
doaj +3 more sources
Small-sized shiny sclerotic plaques: Think early morphea
European Journal of Inflammation, 2022 Morphea is a rare fibrosing disorder of the skin and underlying tissues. To date, the size of morphea has not been adequately discussed. Here, we report two cases of small-sized superficial circumscribed morphea.
Hiroki Hashimoto, Takeshi Nakahara
doaj +1 more source
Dermatopathology, 2022 Morphea profunda or subcutaneous (deep) morphea is a variant of localized morphea, characterized by one or more ill-defined, deep sclerotic plaque. Preferential sites are the abdomen, trunk, sacral area, or extremities.
Angelo Cassisa, Margherita Vannucchi
doaj +1 more source
Lipoatrophic linear morphea in a 5-year-old girl: A novel variant?
Indian Journal of Paediatric Dermatology, 2021 Introduction: Morphea profunda or subcutaneous morphea is a variant of morphea in which inflammation and sclerosis found in deep dermis, subcutaneous tissue, fascia or muscle.
Vibhu Mendiratta +3 more
doaj +1 more source