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Association of Bullous Lichen Sclerosus and Morphea [PDF]

open access: yesClinical Case Reports
Lichen sclerosus (LSc) is an inflammatory skin disease of unknown etiology. The coexistence of LSc and morphea in the same lesion is uncommon but exists. Also, there exist a few rare cases of bullous LSc–generalized morphea overlap syndrome.
Seyyede Zeinab Azimi   +3 more
doaj   +3 more sources

Is adiponectin involved in morphea pathogenesis? – first observational study [PDF]

open access: yesFrontiers in Immunology
BackgroundMorphea is a chronic inflammatory condition characterized by fibrosis of the skin and/or subcutaneous tissues. Adiponectin is an adipokine known for its anti-inflammatory and antifibrotic properties.
Adriana Polańska   +5 more
doaj   +2 more sources

Laser therapy in superficial morphea lesions – indications, limitations and therapeutic alternatives [PDF]

open access: yesJournal of Mind and Medical Sciences, 2020
Morphea or localized scleroderma is an uncommon autoimmune and inflammatory disease which affects patients of any age. Even if morphea lesions present systemic symptoms as myalgias or arthritis, it is distinct from systemic sclerosis because it does not ...
Alin Laurentiu Tatu   +4 more
doaj   +2 more sources

Profiling of Toll-like Receptors and Related Signaling Mediators in the Pathogenesis of Morphea [PDF]

open access: yesDermatology Practical & Conceptual
Introduction: Morphea, also known as localized scleroderma, is a rare fibrosing inflammatory disease of unknown pathogenesis. Objectives: Although the genetic basis for morphea is important, the evaluation of Toll-like receptors (TLR) in this disease ...
Hilal Ayvaz Celik   +4 more
doaj   +2 more sources

A Patient With Plaque Type Morphea Mimicking Systemic Lupus Erythematosus [PDF]

open access: yesActa Medica Indonesiana, 2015
Morphea is an uncommon connective tissue disease with the most prominent feature being thickening or fibrosis of the dermal without internal organ involvement. It is also known as a part of localized scleroderma. Based on clinical presentation and depth
Wardhana Wardhana, EA Datau
doaj   +5 more sources

Generalized morphea following radiotherapy for an intracranial tumor

open access: diamondIndian Journal of Dermatology, 2016
Morphea is a localized scleroderma variety which can be circumscribed or generalized and is characterized by sclerotic plaques developing on trunk and limbs. Surgery and radiation have been implicated as etiological factors for the development of morphea.
Shrenik Balegar   +4 more
doaj   +2 more sources

Morphea simulating paucibacillary leprosy clinically and histopathologically

open access: diamondIndian Journal of Dermatology, 2013
Clinically and histopathologically paucibacillary leprosy shows similar features with initial morphea. In this case we report a 24 yr-old male patient who presented to our dermatology department with diagnosed paucibacillary leprosy by his local ...
José Saulo Torres Delgado   +3 more
doaj   +2 more sources

Linear morphea distributed along radial nerve with high incidence of neuromusculoskeletal disorders: A single-center case series [PDF]

open access: yesHeliyon
Linear morphea is the most disabling subtype of morphea, which may cause a series of excutaneous manifestations and sequelae. To futher explore the clinical characteristics of linear morphea, we conducted a retrospective study of 22 patients diagnosed ...
Xiuyuan Wang   +5 more
doaj   +2 more sources

Muscle weakness in a 4-year-old girl: A rare presentation of deep morphea

open access: yesIndian Journal of Paediatric Dermatology, 2021
Introduction: Morphea is a rare fibrosing disorder of the skin and underlying tissues. Deep morphea involves the deep dermis, subcutis, fascia, muscle, and bone. The above structures may be involved independently or in combination.
Mary Augustine, Sumedha Ballal
doaj   +1 more source

Autoantigen microarrays reveal myelin basic protein autoantibodies in morphea

open access: yesJournal of Translational Medicine, 2022
Background Morphea is an autoimmune, sclerosing skin disorder. Despite the recent emphasis on immune dysregulation in morphea, the role of autoantibodies in morphea pathogenesis or utility as biomarkers are poorly defined.
Jane L. Zhu   +12 more
doaj   +1 more source

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