Results 181 to 190 of about 7,741 (242)

Effect of UV-A1 Phototherapy Treatment on Scleroderma: A Systematic Review. [PDF]

Cureus
Nagy S, Tehrani L, Kesselman MM.
europepmc   +1 more source

Upadacinib for the Treatment of Refractory Morphea. [PDF]

Australas J Dermatol
Maione V, Rovaris S, Romanò C, Bighetti S, Ghini I, Bettolini L.   +5 more
europepmc   +1 more source

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Development and Validation of the Morphea Activity Measure in Patients With Pediatric Morphea.

JAMA dermatology, 2023
Importance Morphea is an insidious inflammatory disorder of the skin and deeper tissues. Determining disease activity is challenging yet important to medical decision-making and patient outcomes.
M. García-Romero, M. Tollefson, E. Pope, H. Brandling-Bennett, A. Paller, E. Keimig, L. Arkin, K. Wanat, S. Humphrey, V. Werth, V. Oza, H. Jacobe, N. Fett, K. Cordoro, Isabel Medina-Vera, Y. Chiu   +15 more
semanticscholar   +1 more source

Ultrasound Morphea Activity Scoring (US‐MAS): Modified US‐MAS

Journal of ultrasound in medicine, 2023
Morphea, an autoimmune connective tissue disease that affects the skin, can be supported by color Doppler ultrasound in its diagnosis and assessment of activity.
X. Wortsman, C. Vera-Kellet
semanticscholar   +1 more source

Clinical characteristics associated with musculoskeletal extracutaneous manifestations in pediatric and adult morphea: a prospective, cohort study.

Journal of Investigative Dermatology, 2023
Morphea is an autoimmune condition of the skin associated with functional sequelae resulting from musculoskeletal involvement. Systematic investigation of risk for musculoskeletal involvement is limited, particularly in adults.
Henry W. Chen, A. Walker, Amy B Stein, Sojung L Chen, K. Schollaert-Fitch, K. Torok, H. Jacobe   +6 more
semanticscholar   +1 more source

Pediatric Morphea

Dermatologic Clinics, 2013
This article outlines the epidemiology, pathogenesis, clinical presentation, diagnosis, and treatment of childhood morphea. Also known as localized scleroderma, morphea is a fibrosing disorder of the skin and subcutaneous tissues. Morphea is differentiated from systemic sclerosis (scleroderma) based on the absence of sclerodactyly, Raynaud phenomenon ...
John C Browning
exaly   +3 more sources

JAK–STAT pathway is involved in cutaneous sclerosis processes: Generalized morphea successfully treated with baricitinib

Journal of dermatology (Print), 2023
Morphea is a connective tissue disease causing skin thickening and fibrosis that impact patients' quality of life. Standard immunosup-pressant treatments have limited efficacy.
C. Labrandero Hoyos, R. Peñuelas Leal, Andrés Grau Echevarría, J. Lorca Spröhnle, Jorge Magdaleno Tapial, Malena Finello, D. Imbernon, Amparo Pérez Ferriols, V. Zaragoza Ninet   +8 more
semanticscholar   +1 more source

Janus kinase inhibitors for treatment of morphea and systemic sclerosis: A literature review

Dermatologic Therapy, 2022
Morphea and systemic sclerosis (SSc) are rare disorders of connective tissue characterized by increased skin thickness and fibrosis, with current treatment options having variable efficacies, many with limited therapeutic benefit.
S. McGaugh, P. Kallis, A. De Benedetto, Renee M Thomas   +3 more
semanticscholar   +1 more source

Gene expression signatures in inflammatory and sclerotic morphea skin and sera distinguish morphea from systemic sclerosis.

Journal of Investigative Dermatology, 2023
Morphea is an inflammatory fibrotic disorder of the skin that has been likened to systemic sclerosis (SSc). We sought to examine the molecular landscape of morphea by examining lesional skin gene expression and blood biomarkers and comparing the gene ...
Henry W. Chen, Jane L. Zhu, V. Martyanov, L. Tsoi, Michael E. Johnson, G. Barber, Dillon Popovich, J. O’Brien, J. Coias, N. Cyrus, N. Malviya, S. Florez-Pollack, E. Kunzler, G. Hosler, J. Gudjonsson, D. Khanna, M. Whitfield, H. Jacobe   +17 more
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