Results 51 to 60 of about 8,297 (249)

S1‐Guideline for diagnosis and therapy of necrobiosis lipoidica

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Necrobiosis lipoidica (NL) is a rare granulomatous skin disease of unknown etiology that occurs frequently in association with diabetes mellitus and other comorbidities. The predilection site is the lower leg, particularly the pretibial areas. The exact pathogenesis remains unclear.
Cornelia Erfurt‐Berge, Regina Renner, Melanie Peckruhn, Jörg Tittelbach, Dorothea Terhorst‐Molawi, Friederike Kauer, Joachim Dissemond   +6 more
wiley   +1 more source

Dermatology 2.0: Precision medicine for inflammatory skin diseases

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Digital immune mapping of transcriptomics profiles from inflammatory skin disease biopsies enables precise molecular diagnosis, quantification of immune modules and personalized therapy selection by matching dominant immune signatures to targeted treatments.
Jeremy Di Domizio, Antoine Girardin, Curdin Conrad, Teofila Seremet, Michel Gilliet   +4 more
wiley   +1 more source

Chronic Morel‐Lavallée Lesion in a Pediatric Competitive Dancer: A Case Report and Literature Review

Pediatric Dermatology, EarlyView.
ABSTRACT Morel‐Lavallée lesions (MLLs) are rare internal degloving injuries resulting from shearing trauma, with few reported cases in the pediatric population. We present the case of a 16‐year‐old female competitive dancer with persistent right knee pain, skin atrophy, and ecchymosis after trauma sustained during a national dance competition, with MRI
Cameron Coakes, Kent Axcell, Andrea L. Zaenglein, Timothy Hahn   +3 more
wiley   +1 more source

Janus Kinase Inhibitors for the Treatment of Pediatric Morphea: A Systematic Review

Pediatric Dermatology, EarlyView.
ABSTRACT Morphea, also known as localized scleroderma (LoS), is an inflammatory, fibrosing dermatologic disorder of the skin and underlying tissues with associated comorbidities including joint contractures, limb‐length discrepancies, and inflammatory arthropathy occurring more commonly in children.
Alexa Moschella, Celina DeBiasio, Carmen Liy‐Wong   +2 more
wiley   +1 more source

Concentrations of metalloproteinase-1 in patients with morphea treated with phototherapy: a preliminary study [PDF]

, 2022
Anna Malewska-Woźniak, Martha Lodyga, Zygmunt Adamski   +2 more
openalex   +1 more source

Prevalence and Clinical Characteristics of Systemic Sclerosis in Alaska Native and American Indian Peoples in Alaska

ACR Open Rheumatology, Volume 8, Issue 1, January 2026.
Objective Systemic sclerosis (SSc) is known to exhibit significant epidemiologic and clinical variation. This study aimed to describe the clinical and epidemiologic characteristics of SSc in Alaska Native and American Indian (AN/AI) individuals in Alaska.
Vivek R. Mehta, Peter Holck, Tammy L. Choromanski, Amy Wilson, Flora Lee, Elizabeth D. Ferucci   +5 more
wiley   +1 more source

Case of generalized morphea complicated with systemic sclerosis

Dermatology Reports, 2021
Dear Editor, Localized scleroderma (LSc; morphea) is a rare fibrosing disease of the skin and underlying tissues, which is different from systemic sclerosis (SSc).
Soichiro Sawamura, Katsunari Makino, Hitomi Nakashima, Takamitsu Makino, Satoshi Fukushima   +4 more
doaj   +1 more source

Bullous hemorrhagic lichen sclerosus of the breast: a report of two cases and review of the literature [PDF]

, 2019
Lichen sclerosus (LS) is a chronic dermatologic condition characterized by atrophic porcelain-appearing plaques that can cause intense discomfort and eventually lead to destruction of local architecture.
Kroger, Kathleen T, Monjazeb, Seena, Ross, Lindy S, Ryan, Michael P   +3 more
core  

Extensive morphea profunda with autoantibodies and benign tumors: A rare case report

Indian Dermatology Online Journal, 2012
The term deep morphea describes a variant of morphea (localised scleroderma) in which inflammation and sclerosis are found in the deep dermis, panniculus, fascia or superficial muscle. It is sometimes associated with autoantibodies. We report the case of
Leelavathy Budamakuntla, Dipali Malvankar   +1 more
doaj   +1 more source

Mapping the Tissue‐of‐Origins of Mesenchymal Stromal Cells in Injury Repair

Advanced Science, Volume 13, Issue 3, 14 January 2026.
This study maps mesenchymal stromal cells (MSCs) across multiple tissues, revealing that bone marrow–derived MSCs mobilize monocytes via CCL2 to promote systemic inflammation but do not migrate to distant organs to form fibrotic or tumor stroma. Instead, local MSCs dominate tissue remodeling, suggesting a “two‐hit” model linking systemic inflammation ...
Xinyu Thomas Tang, Yiming Liam Liu, Yidi Augenstern Du, Shan−Shan Wang, Bo O. Zhou   +4 more
wiley   +1 more source