S1‐Guideline for diagnosis and therapy of necrobiosis lipoidica
Summary Necrobiosis lipoidica (NL) is a rare granulomatous skin disease of unknown etiology that occurs frequently in association with diabetes mellitus and other comorbidities. The predilection site is the lower leg, particularly the pretibial areas. The exact pathogenesis remains unclear.
Cornelia Erfurt‐Berge +6 more
wiley +1 more source
Dermatology 2.0: Precision medicine for inflammatory skin diseases
Digital immune mapping of transcriptomics profiles from inflammatory skin disease biopsies enables precise molecular diagnosis, quantification of immune modules and personalized therapy selection by matching dominant immune signatures to targeted treatments.
Jeremy Di Domizio +4 more
wiley +1 more source
Chronic Morel‐Lavallée Lesion in a Pediatric Competitive Dancer: A Case Report and Literature Review
ABSTRACT Morel‐Lavallée lesions (MLLs) are rare internal degloving injuries resulting from shearing trauma, with few reported cases in the pediatric population. We present the case of a 16‐year‐old female competitive dancer with persistent right knee pain, skin atrophy, and ecchymosis after trauma sustained during a national dance competition, with MRI
Cameron Coakes +3 more
wiley +1 more source
Janus Kinase Inhibitors for the Treatment of Pediatric Morphea: A Systematic Review
ABSTRACT Morphea, also known as localized scleroderma (LoS), is an inflammatory, fibrosing dermatologic disorder of the skin and underlying tissues with associated comorbidities including joint contractures, limb‐length discrepancies, and inflammatory arthropathy occurring more commonly in children.
Alexa Moschella +2 more
wiley +1 more source
Concentrations of metalloproteinase-1 in patients with morphea treated with phototherapy: a preliminary study [PDF]
Anna Malewska-Woźniak +2 more
openalex +1 more source
Objective Systemic sclerosis (SSc) is known to exhibit significant epidemiologic and clinical variation. This study aimed to describe the clinical and epidemiologic characteristics of SSc in Alaska Native and American Indian (AN/AI) individuals in Alaska.
Vivek R. Mehta +5 more
wiley +1 more source
Case of generalized morphea complicated with systemic sclerosis
Dear Editor, Localized scleroderma (LSc; morphea) is a rare fibrosing disease of the skin and underlying tissues, which is different from systemic sclerosis (SSc).
Soichiro Sawamura +4 more
doaj +1 more source
Bullous hemorrhagic lichen sclerosus of the breast: a report of two cases and review of the literature [PDF]
Lichen sclerosus (LS) is a chronic dermatologic condition characterized by atrophic porcelain-appearing plaques that can cause intense discomfort and eventually lead to destruction of local architecture.
Kroger, Kathleen T +3 more
core
Extensive morphea profunda with autoantibodies and benign tumors: A rare case report
The term deep morphea describes a variant of morphea (localised scleroderma) in which inflammation and sclerosis are found in the deep dermis, panniculus, fascia or superficial muscle. It is sometimes associated with autoantibodies. We report the case of
Leelavathy Budamakuntla +1 more
doaj +1 more source
Mapping the Tissue‐of‐Origins of Mesenchymal Stromal Cells in Injury Repair
This study maps mesenchymal stromal cells (MSCs) across multiple tissues, revealing that bone marrow–derived MSCs mobilize monocytes via CCL2 to promote systemic inflammation but do not migrate to distant organs to form fibrotic or tumor stroma. Instead, local MSCs dominate tissue remodeling, suggesting a “two‐hit” model linking systemic inflammation ...
Xinyu Thomas Tang +4 more
wiley +1 more source

