Results 71 to 80 of about 8,335 (248)

Twardzina ograniczona pęcherzowa – przedstawienie dwóch przypadków, trudności terapeutyczne

Przegląd Dermatologiczny, 2011
tissue disease. The main symptoms are atrophy and fibrosis of the connectivetissue stroma, preceded by changes in the small blood vessels.Pathogenesis of morphea is still unknown.
Dorota Krasowska, Aldona Pietrzak, Bartłomiej Wawrzycki, Joanna Gładysz, Grażyna Chodorowska, Katarzyna Kozłowicz   +5 more
doaj  

Порівняльна оцінка особливостей морфологічного перебігу уражень шкіри при обмеженій (бляшковій) та системній склеродермії [PDF]

, 2016
В біоптатах ураженої шкіри хворих на бляшкову (n = 35) та системну (n = 10) склеродермію констатовано подібні показники патоморфологічних і нейроморфологічних порушень та експресії 15 імуногістохімічних маркерів (CD3, CD8, CD20, CD79α, CD68, CD1α, CD34 ...
Горбунцов, В.В., Романенко, К.В.   +1 more
core  

Selective deletion of PPARβ/δ in fibroblasts causes dermal fibrosis by attenuated LRG1 expression. [PDF]

, 2018
Connective tissue diseases of the skin are characterized by excessive collagen deposition in the skin and internal organs. Fibroblasts play a pivotal role in the clinical presentation of these conditions.
Chan, JSK, Chen, J.P., Chiba, S., Koh, NJN, Ng, X.R., Pal, M., Phua, T., Sng, M.K., Tan, C.K., Tan, EHP, Tan, N.S., Teo, Z., Tnay, Y.L., Tong, BMK, Wahli, W., Wang, X., Wee, JWK, Zhu, P.   +17 more
core   +4 more sources

Linear morphea distributed along radial nerve with high incidence of neuromusculoskeletal disorders: A single-center case series

Heliyon
Linear morphea is the most disabling subtype of morphea, which may cause a series of excutaneous manifestations and sequelae. To futher explore the clinical characteristics of linear morphea, we conducted a retrospective study of 22 patients diagnosed ...
Xiuyuan Wang, Xue Han, Feifei Hu, Xinzhi Xu, Junxia Huang, Ji Yang   +5 more
doaj   +1 more source

Drooling as a Red Flag: Insights From a Case Series in Severe Dermatomyositis With Literature Review

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Dermatomyositis (DM) is a rare idiopathic inflammatory disease characterized by progressive proximal muscle weakness and distinctive dermatologic manifestations. Although dysphagia is a recognized complication of oropharyngeal muscle involvement, drooling (sialorrhea) is infrequently described and may be a marker of severe disease.
Alireza Mirzamohamadi, Shokufe Sadeghi, Yalda Nilipour, Somayeh Motamed, Vahid Ardestani Rostami, Ahmadreza Jamshidi, Masoomeh Akhlaghi, Hoda Kavoosi, Majid Alikhani, Seyedeh Tahereh Faezi   +9 more
wiley   +1 more source

Severe alopecia complicating systemic sclerosis [PDF]

, 2015
Aims: To describe a case of systemic sclerosis (SSc) associated with severe alopecia areata (AA) responsive to topical and systemic treatments, including vasoactive and immunosuppressive drugs (mycophenolate mofetil). Presentation of the Case: A 56 year
Cassone, Giulia, COLACI, Michele, FERRI, Clodoveo, GIUGGIOLI, DILIA   +3 more
core   +1 more source

Haploinsufficiency of brain‐specific kinase BRSK1 causes epilepsy and neurodevelopmental disorders

Epilepsia, Volume 66, Issue 12, Page 5033-5054, December 2025.
Abstract Objective The BRSK1 gene encodes brain‐specific serine/threonine kinase 1 (also known as SAD‐B kinase), which is almost exclusively expressed in the brain and plays critical roles in neuronal polarization, neurotransmitter release, mitochondrial dynamics, and neuronal maturation.
Qi Zhang, Hiroshi Yamanaka, Ping Li, Yingfeng Li, Tian Luo, Miao Xia, Ting Liu, Xueyan Liu, Qing Lu, Bin Yang, Fan He, Kaixian Du, Yousheng Shu, Bo Peng, Yong‐hui Jiang, Yi Wang   +15 more
wiley   +1 more source

Eosinophilic fasciitis: demographics, disease pattern and response to treatment: report of 12 cases and review of the literature [PDF]

, 2007
BACKGROUND: Eosinophilic fasciitis is a rare scleroderma-like illness. The clinical spectrum of the disease has evolved since its initial description. METHODS: We identified all patients diagnosed with eosinophilic fasciitis over the past 10 years at our
Bischoff, Lindsay, Derk, Chris T
core   +2 more sources

Granuloma Annulare and Morphea: Correlation with Borrelia burgdorferi Infections and Chlamydia-related Bacteria

Acta Dermato-Venereologica, 2017
A retrospective study of 109 skin biopsies with granuloma annulare (GA) or morphea histology from patients with suspected tick bite was performed. Biopsies were tested for cutaneous Borrelia burgdorferi DNA using PCR.
Lauri Tolkki, Kati Hokynar, Seppo Meri, Jaana Panelius, Mirja Puolakkainen, Annamari Ranki   +5 more
doaj   +1 more source

Differential expression of secreted factors SOSTDC1 and ADAMTS8 cause pro-fibrotic changes in linear morphoea fibroblasts [PDF]

, 2018
This is the peer reviewed version of the following article: Badshah, I. I., et al. "Differential expression of secreted factors SOSTDC1 and ADAMTS8 cause pro-fibrotic changes in linear morphoea fibroblasts." British Journal of Dermatology 0(ja)., which ...
Badshah, I. I., Brown, S., Harper, J., Inman, G., Kinsler, V., O'Shaughnessy, R., Rose, A., Sebire, N., Way, B., Weibel, L.   +9 more
core   +4 more sources