Results 71 to 80 of about 8,275 (249)

The Aetiology of Elevated Total Serum Immunoglobulin E in Children

open access: yesActa Paediatrica, Volume 114, Issue 11, Page 2993-2999, November 2025.
ABSTRACT Aim The paucity of real‐world data on the aetiology of elevated total serum immunoglobulin E (TS‐IgE) in children afflicts families and health care systems with diagnostic uncertainty. We explored a cohort of children with TS‐IgE levels over 1000 kU/L, focusing on the prevalence of atopic and non‐atopic conditions, the aetiology of extremely ...
Aliisa Ärölä   +2 more
wiley   +1 more source

Linear morphea distributed along radial nerve with high incidence of neuromusculoskeletal disorders: A single-center case series

open access: yesHeliyon
Linear morphea is the most disabling subtype of morphea, which may cause a series of excutaneous manifestations and sequelae. To futher explore the clinical characteristics of linear morphea, we conducted a retrospective study of 22 patients diagnosed ...
Xiuyuan Wang   +5 more
doaj   +1 more source

Riociguat for the treatment of pulmonary arterial hypertension associated with connective tissue disease: results from PATENT-1 and PATENT-2 [PDF]

open access: yes, 2016
BACKGROUND: The 12-week, phase III Pulmonary Arterial hyperTENsion sGC-stimulator Trial (PATENT)-1 study investigated riociguat in patients with pulmonary arterial hypertension (PAH).
Boeckenhoff, A   +10 more
core   +1 more source

Hyalase in Dermatology: Applications Beyond Filler Management

open access: yesJournal of Cosmetic Dermatology, Volume 24, Issue 11, November 2025.
ABSTRACT Background Hyaluronic acid (HA) is a key extracellular matrix component in the skin. Hyaluronidase is an enzyme that breaks down HA into monosaccharides. The FDA has approved this enzyme for hypodermoclysis, drug absorption enhancement, and subcutaneous urography.
Saba Hasanzadeh   +6 more
wiley   +1 more source

Twardzina ograniczona pęcherzowa – przedstawienie dwóch przypadków, trudności terapeutyczne

open access: yesPrzegląd Dermatologiczny, 2011
tissue disease. The main symptoms are atrophy and fibrosis of the connectivetissue stroma, preceded by changes in the small blood vessels.Pathogenesis of morphea is still unknown.
Dorota Krasowska   +5 more
doaj  

Eosinophilic fasciitis: demographics, disease pattern and response to treatment: report of 12 cases and review of the literature [PDF]

open access: yes, 2007
BACKGROUND: Eosinophilic fasciitis is a rare scleroderma-like illness. The clinical spectrum of the disease has evolved since its initial description. METHODS: We identified all patients diagnosed with eosinophilic fasciitis over the past 10 years at our
Bischoff, Lindsay, Derk, Chris T
core   +2 more sources

Severe alopecia complicating systemic sclerosis [PDF]

open access: yes, 2015
Aims: To describe a case of systemic sclerosis (SSc) associated with severe alopecia areata (AA) responsive to topical and systemic treatments, including vasoactive and immunosuppressive drugs (mycophenolate mofetil). Presentation of the Case: A 56 year
Cassone, Giulia   +3 more
core   +1 more source

Early morphea simulating patch-stage mycosis fungoides in two cases

open access: yesDermatology Reports, 2018
Morphea is a skin disorder characterized by thickening of dermis and subcutaneous tissues and loss of adnexal structures. In the early inflammatory stage of morphea, diagnostic histological findings are absent and this may lead to confusion with other ...
Hamid R. Ghasemi Basir   +3 more
doaj   +1 more source

Histopathology of morphea: Sensitivity of various named signs, a retrospective study

open access: yesIndian Journal of Pathology and Microbiology, 2020
Background: Morphea or localized scleroderma is characterized histopathologically by sclerosis, fibrosis, and atrophy of the skin and subcutaneous tissue.
Rashmi Jindal   +2 more
doaj   +1 more source

Morphea on the breast and pregnancy

open access: yesThe Pan African Medical Journal, 2013
Morphea is an uncommon, indolent, dermatologic disorder characterized by dermal fibrosis and collagen deposition. Its appearance during pregnancy is rare.
Loubna Benchat, Fatima Zahra Mernissi
doaj   +1 more source

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