Results 71 to 80 of about 10,146,942 (315)

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

REGULAR MORPHOLOGY VS. PROSODIC MORPHOLOGY? THE CASE OF TRUNCATIONS IN GERMAN [PDF]

open access: yesJournal of Germanic Linguistics, 2001
This paper is a study of the morphology and phonology of truncations in German (also known as i-Bildungen) within the framework of Optimality Theory. Truncations are shown to constitute a widespread and productive morphological pattern in Modern Standard German.
openaire   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The case system of the Vilamovicean adjective – from description to explanation

open access: yesStellenbosch Papers in Linguistics, 2013
The present paper offers a detailed description and analysis of the adjectival declensional patterns in the Modern Vilamovicean language. Modern Vilamovicean possesses six declensional patterns, restricted to distinct environments, that, from a ...
Andrason, Alexander
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Myoepithelial carcinoma arising in an adenomyoepithelioma of the breast: A case report of a rare entity

open access: yesIndian Journal of Pathology and Microbiology, 2010
Adenomyoepithelioma of the breast is a rare tumor. Malignant change arising in this lesion is infrequent and only a few cases have been reported. We discuss a case of a 56-year-old female presenting with a firm breast mass, which was interpreted as ...
Khurana Anuj, Jalpota Yashpal
doaj  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

The fourth-stage autoinfective larva of Strongyloides stercoralis: redescription and diagnostic implications

open access: yesJournal of Clinical Microbiology
Human strongyloidiasis is often underdiagnosed or misdiagnosed, which can relate to a lack of knowledge or recognition of the importance of particular developmental/larval stages of Strongyloides stercoralis in making an accurate diagnosis using ...
Huan Zhao   +8 more
doaj   +1 more source

PECULIARITIES OF MORPHOLOGICAL VERIFICATION IN BREAST CANCER [PDF]

open access: yesСаратовский научно-медицинский журнал, 2008
80 case histories of patients with breast cancer were analyzed. During the preoperative examination with objective and instrumental examination methods used the malignant process was suspected but no morphological verification was received.
L.F. Zhandarova   +2 more
doaj  

DIFFICULTIES OF DIAGNOSTICS AND CHOICE OF SURGICAL APPROACH IN PATIENTS WITH DUCTAL CHOLANGIOCARCINOMA

open access: yesВестник хирургии имени И.И. Грекова, 2017
Diagnostics and treatment of ductal cholangiocarcinoma is an actual and complicated problem of modern hepatopancreatobiliary surgery. The data of preoperative examination using modern methods weren’t always well-defined. This fact didn’t allow clinicians
D. A. Granov, I. V. Timergalin
doaj   +1 more source

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