Results 51 to 60 of about 750,746 (278)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Morphology investigation of sulfur-polymer composite [PDF]
, 2023 This research evaluates the effects of the acid environment on sulfur-polymer composite. For this purpose, a morphology investigation consisting of mathematical morphology analysis and SEM analysis was performed. Based on the obtained results, insignificant changes in the pore system of sulfur-polymer composite in terms of deterioration, pore ...
Vlahović, Milica +6 more
openaire +1 more source
A phase-field study of elastic stress effects on phase separation in ternary alloys
, 2019 Most of the commercially important alloys are multicomponent, producing multiphase microstructures as a result of processing. When the coexisting phases are elastically coherent, the elastic interactions between these phases play a major role in the ...
Bhattacharya, Saswata, Sugathan, Sandeep
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Differences in the Morphological Characteristics and Body Composition of Football Players of HSC Zrinjski Mostar and FC Siroki Brijeg in Bosnia and Herzegovina [PDF]
Sport Mont, 2018 The aim of this research was to determine the diff erences among the top football players of the two clubs in Bosnia and Herzegovina, HSC Zrinjski Mostar and FC Siroki Brijeg in the morphological characteristics and body composition.
Marin Corluka +5 more
doaj +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Edukasi: Jurnal Pendidikan dan Pengajaran, 2016 The objectives of the study are 1) to find out the types of morphological errors in students of MAN 2 Palembang in writing narrative composition, 2) to find out the most frequent type of morphological errors made by eleventh grade students of MAN 2 ...
Sahran Imam
doaj
The effects of graded levels of calorie restriction : II. Impact of short term calorie and protein restriction on circulating hormone levels, glucose homeostasis and oxidative stress in male C57BL/6 mice [PDF]
, 2015 This work was supported by BBSRC BB009953/1 awarded to JRS and SEM. PK and CD were funded by the Erasmus exchange programme. JRS, SEM, DD, CG, LC, JJDH, YW, DELP, DL and AD are members of the BBSRC China Partnership Award, BB/J020028/1.Peer ...
Chen, Luonan +12 more
core +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source